Results 211 to 220 of about 111,262 (297)

QuickProt: A Fast and Accurate Homology‐Based Protein Annotation Tool for Non‐Model Organisms to Advance Comparative Genomics

Molecular Ecology Resources, Volume 26, Issue 2, February 2026.
ABSTRACT The rapid growth of genome sequencing has outpaced the development of efficient annotation tools, especially for species lacking transcriptome data. To address this challenge, we present QuickProt, a fast, accurate and user‐friendly homology‐based protein annotation tool.
Guisen Chen, Hehe Du, Zhenjie Cao, Ying Wu, Chen Zhang, Yongcan Zhou, Jingqun Ao, Yun Sun, Zihao Yuan   +8 more
wiley   +1 more source

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler, Ingrid Richter, Katharina Dornblut, Alicia Scharf, Christian Hertweck   +4 more
wiley   +2 more sources

Embryonic Development of Caenorhabditis elegans Sense Organs. [PDF]

J Comp Neurol
Wexler LR, Kolotuev I, Heiman MG.
europepmc   +1 more source

Copper Oxide Nanoparticles Impact Several Toxicological Endpoints and Cause Neurodegeneration in Caenorhabditis elegans

, 2016
Michael J. Mashock, Tyler Zanon, Anthony D. Kappell, Lisa N. Petrella, Erik C. Andersen, Krassimira R. Hristova   +5 more
openalex   +2 more sources

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

High-throughput developmental assay of cold tolerance in <i>Caenorhabditis elegans</i>. [PDF]

MicroPubl Biol
Peake AL, Jhaveri NS, Andersen EC, Stinchcombe JR.   +3 more
europepmc   +1 more source

STUDIES ON THE DEVELOPMENT OF CAENORHABDITIS ELEGANS USING TEMPERATURE SENSITIVE MUTANTS ON CHROMOSOME 5.

, 1979
Kim R. C. Riekki
openalex   +1 more source

Reduced Proteasome Degradation of HSF‐1 Shifts Protein Stress Management With Age in Caenorhabditis elegans

Aging Cell, Volume 25, Issue 2, February 2026.
Ageing C. elegans prioritises chronic protein stress protection over acute stress response by coordinating HSF‐1 activity. Decreased PBS‐7 binding in aged worms reduces HSF‐1 degradation, enhancing its ability to upregulate protective factors against accumulating protein aggregates while simultaneously suppressing its activation under acute heat shock.
Hongwei Wang, Fengzhen Sun, Zhidong He, Xiaojie Wang, Hao Liu, Mengjiao Song, Qingxia Chen, Zhixue Li, Ligang Wu, Xiumin Yan, Xueliang Zhu, Yidong Shen   +11 more
wiley   +1 more source

Drug screens using the nematode Caenorhabditis elegans. [PDF]

Genetics
Roy PJ.
europepmc   +1 more source

Loss of E3 ligase HvST1 function substantially increases distal crossover frequency

New Phytologist, Volume 249, Issue 3, Page 1325-1341, February 2026.
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr, Sybille Ursula Mittmann, Luke Ramsay, Dominika Lewandowska, Abdellah Barakate, Malcolm Macaulay, Nicola McCallum, Robbie Waugh, Isabelle Colas   +8 more
wiley   +1 more source