Results 221 to 230 of about 279,189 (378)

The pace and shape of ant ageing

open access: yesBiological Reviews, EarlyView.
ABSTRACT Ants have been proposed as good models to study ageing and the effects of extrinsic mortality because of their long lifespans and plasticity of ageing within species. We discuss how age‐dependent extrinsic mortality might influence queen lifespan, and how the effect of age‐independent extrinsic mortality needs further study, accounting for ...
Luisa M. Jaimes‐Nino, Jan Oettler
wiley   +1 more source

Plasticity in climate change responses

open access: yesBiological Reviews, EarlyView.
ABSTRACT Recent research has shown that climate change can both induce and modulate the expression of plastic traits but our understanding of the role of phenotypic plasticity as an adaptive response to climate change is limited. In this review, we dissect the mechanisms and impact of phenotypic plasticity as a response to accumulating climatic ...
Angelika Stollewerk   +18 more
wiley   +1 more source

Elucidating the Role and Mechanism of Alpha‐Enolase in Senescent Amelioration via Metabolic Reprogramming

open access: yesCell Proliferation, EarlyView.
KB2764 interacted with alpha‐enolase (ENO1) and pyruvate kinase M (PKM), ultimately leading to PKM phosphorylation of ENO1. KB2764 consequently increased mitochondrial ATP production and decreased glycolysis dependence. Furthermore, the action of KB2764 extends its application to extend the lifespan of Caenorhabditis elegans.
Yun Haeng Lee   +13 more
wiley   +1 more source

Unraveling the functional dynamics of Caenorhabditis elegans stress‐responsive omega class GST‐44

open access: yesThe FEBS Journal, EarlyView.
Omega‐class glutathione S‐transferases (GSTs) are integral to redox regulation and cellular stress responses. This study characterized GST‐44 in Caenorhabditis elegans, revealing its predominant expression in the intestine and excretory H‐cell, with significant upregulation under various stress conditions.
Charlotte Sophia Kaiser   +9 more
wiley   +1 more source

Transcription‐coupled repair: tangled up in convoluted repair

open access: yesThe FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher   +3 more
wiley   +1 more source

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