Results 51 to 60 of about 118,692 (314)

Identification and characterization of agrin in "Caenorhabditis elegans" [PDF]

, 2006
Agrin is a large basement membrane (BM) proteoglycan expressed in many tissues in vertebrates, with particularly important function at the neuromuscular junction (NMJ) where it clusters acetylcholine receptors (AChRs) and maintains structural stability ...
Hrus, Ana
core   +1 more source

CAENORHABDITIS ELEGANS AND ANGIOGENESIS

TURKISH MEDICAL STUDENT JOURNAL, 2019
Abstract: Angiogenesis is sprouting of new capillaries from already existing ones. It is a dynamic process that can be seen in every phase of human life. It is among the dynamic mechanisms of both physiological and pathological processes. Vascular endothelial growth factor is one of the many molecules that play a role in angiogenesis.
KILIÇÇALAN, İbrahim, ERKOVAN, Abdulbaki, ŞEN, Emine   +2 more
openaire   +3 more sources

Transcriptional adaptation in Caenorhabditis elegans

eLife, 2020
Transcriptional adaptation is a recently described phenomenon by which a mutation in one gene leads to the transcriptional modulation of related genes, termed adapting genes. At the molecular level, it has been proposed that the mutant mRNA, rather than the loss of protein function, activates this response.
Vahan Serobyan, Zacharias Kontarakis, Mohamed A El-Brolosy, Jordan M Welker, Oleg Tolstenkov, Amr M Saadeldein, Nicholas Retzer, Alexander Gottschalk, Ann M Wehman, Didier YR Stainier   +9 more
openaire   +7 more sources

Recent progresses on anti-aging compounds and their targets in Caenorhabditis elegans

Translational Medicine of Aging, 2019
Searching for drugs that extend healthy lifespan and the subsequent analysis of their mechanisms of action is a crucial aspect for aging research. However, identifying both longevity-enhancing drugs and their corresponding targets is challenging.
Eun Ji E. Kim, Seung-Jae V. Lee
doaj   +1 more source

Protein disulfide isomerase activity is essential for viability and extracellular matrix formation in the nematode Caenorhabditis elegans. [PDF]

, 2007
Protein disulfide isomerase (PDI) is a multifunctional protein required for many aspects of protein folding and transit through the endoplasmic reticulum.
Page, Antony P., McCormack, Gillian, Winter, AD, Page, AP, McCormack, G, Winter, Alan D.   +5 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

In silico Evaluation of mirror repeats within ced-9 Gene of Caenorhabditis elegans

Biomedical and Biotechnology Research Journal, 2023
Background: Repetitive elements constitute a significant proportion of metazoan genomes. These elements form different types of unusual structures, such as left-handed Z-DNA, triple-stranded H-DNA, G-quadruplex, and cruciform, and are related to various ...
Mamta Dhankhar, Deepti Yadav, Vikash Bhardwaj   +2 more
doaj   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Drop‐Shaped Optical Microfiber Enabled Biomechanical Sensor

Advanced Science, EarlyView.
A novel microforce sensor based on a drop‐shaped optical microfiber is presented herein, designed to characterize the biomechanical properties of single cells and microscale living organisms, achieving a force resolution of 24 nN. Leveraging its high sensitivity, facile miniaturization, excellent flexibility, and robust mechanical stability, this ...
Yan Xu, Xitao Tu, Haochen Jiang, Jun Mo, Xinyue Zhang, Xiaomin Yue, Limin Tong, Lei Zhang   +7 more
wiley   +1 more source

Progress in Caenorhabditis elegans as a Degenerative Disease Model for Molecular Pathways Studying

Shiyan dongwu yu bijiao yixue
With the acceleration of population aging in China, the number of patients with degenerative diseases has exceeded ten million, urgently requiring efficient mechanism research and drug screening systems.
SUN Han, GUO Peng, YU Xinhe, ZHANG Junqiao, YAO Ying, YANG Wen   +5 more
doaj   +1 more source