Results 61 to 70 of about 118,692 (314)

A Genome-Wide RNAi Screen for Factors Involved in Neuronal Specification in Caenorhabditis elegans.

, 2011
One of the central goals of developmental neurobiology is to describe and understand the multi-tiered molecular events that control the progression of a fertilized egg to a terminally differentiated neuron.
Poole Richard J., Eileen B. Flowers, Bashllari Enkelejda, Flowers Eileen B., Cochella, L, Oliver Hobert, Hobert Oliver, Flowers, EB, Luisa Cochella, Cochella Luisa, Bashllari, E, Hobert, O, Eileen B Flowers, Enkelejda Bashllari, Poole, RJ, Richard J Poole, Richard J. Poole   +16 more
core   +1 more source

Control of pluripotency during the oocyte-to-embryo transition in caenorhabditis elegans [PDF]

, 2015
The germline of Caenorhabditis elegans has been used as a model system to study the control of pluripotency in germ cells: through the mean of a genetic screen, from which most of the results of this thesis derived, different factors involved in the ...
Tocchini, Cristina
core   +1 more source

The Multilayer Connectome of Caenorhabditis elegans

PLOS Computational Biology, 2016
Connectomics has focused primarily on the mapping of synaptic links in the brain; yet it is well established that extrasynaptic volume transmission, especially via monoamines and neuropeptides, is also critical to brain function and occurs primarily outside the synaptic connectome.
Barry Bentley, Robyn Branicky, Christopher L. Barnes, Yee Lian Chew, Eviatar Yemini, Edward T. Bullmore, Petra E. Vértes, William R. Schafer   +7 more
openaire   +8 more sources

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

From small brains to smart machines: translating Caenorhabditis elegans neural circuits into artificial intelligence

Frontiers in Neural Circuits
The hermaphroditic Caenorhabditis elegans, with its fully mapped connectome of 302 neurons, offers a paradigmatic example of how a minimal nervous system governs biotic, adaptive, and context-dependent behaviors.
He Liu, Panpan Zheng, Panpan Zheng, Xuebin Wang   +3 more
doaj   +1 more source

Biology and genome of a newly discovered sibling species of Caenorhabditis elegans

Nature Communications, 2018
Caenorhabditis nematodes are important model organisms. Here, the authors report the biology and genome of Caenorhabditis inopinata, a first sibling species of C. elegans, and develop genetic and molecular techniques for C. inopinata.
Natsumi Kanzaki, Isheng J. Tsai, Ryusei Tanaka, Vicky L. Hunt, Dang Liu, Kenji Tsuyama, Yasunobu Maeda, Satoshi Namai, Ryohei Kumagai, Alan Tracey, Nancy Holroyd, Stephen R. Doyle, Gavin C. Woodruff, Kazunori Murase, Hiromi Kitazume, Cynthia Chai, Allison Akagi, Oishika Panda, Huei-Mien Ke, Frank C. Schroeder, John Wang, Matthew Berriman, Paul W. Sternberg, Asako Sugimoto, Taisei Kikuchi   +24 more
doaj   +1 more source

A genome-wide library of CB4856/N2 introgression lines of Caenorhabditis elegans

, 2009
Recombinant inbred lines (RILs) derived from Caenorhabditis elegans wild-type N2 and CB4856 are increasingly being used for mapping genes underlying complex traits.
Jan Kammenga, Snoek, L.B., L. Basten Snoek, Emilie Fradin, Riksen, J.A.G., Joost Riksen, Doroszuk, A., Kammenga, J.E., Agnieszka Doroszuk, Fradin, E.   +9 more
core   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

Advanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou, Anran Yan, Haowei Guo, Ping Chen, Qiang Chu   +4 more
wiley   +1 more source

The neurexin superfamily of Caenorhabditis elegans

Gene Expression Patterns, 2011
The neurexin superfamily is a group of transmembrane molecules mediating cell-cell contacts and generating specialized membranous domains in polarized epithelial and nerves cells. We describe here the domain organization and expression of the entire, core neurexin superfamily in the nematode Caenorhabditis elegans, which is composed of three family ...
Haklai-Topper, Liat, Soutschek, Jürgen, Sabanay, Helena, Scheel, Jochen, Hobert, Oliver, Peles, Elior   +5 more
openaire   +3 more sources

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source