Parkinson's disease‐associated protein α‐synuclein can assemble into liquid condensates under strongly perturbed in vitro and in vivo experimental conditions, including high protein concentration, macromolecular crowding, and when attached to various tags with cross‐linking ability.
Simran Arora +1 more
wiley +1 more source
Integrative Transcriptome and Metabolome Analysis Reveals the Regulatory Mechanism Underlying the Potential Antioxidant Activity of Neohesperidin Dihydrochalcone-L-Arginine Complex in <i>Caenorhabditis elegans</i>. [PDF]
Chen P +5 more
europepmc +1 more source
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil +6 more
wiley +1 more source
Heat shock factor-1 alleviates ER-stress in Caenorhabditis elegans. [PDF]
Ahmed S +12 more
europepmc +1 more source
An Unfolding Story: AlphaFold's View on Protein Flexibility
AlphaFold confidence measures allow for detailed proteome‐wide characterization of protein flexibility. All flexibility measures increased substantially in the evolutionary transition from prokaryota to eukaryota. ABSTRACT The AlphaFold confidence measures are related to conformation distribution of the protein.
Gunnar Jeschke
wiley +1 more source
Loss of sphingomyelin synthase-1 does not cause egg retention or locomotion defects in Caenorhabditis elegans. [PDF]
Wang W, Gao X, Pocock R.
europepmc +1 more source
The FAR Protein Family of the Nematode Caenorhabditis elegans [PDF]
Antonio Garofalo +9 more
openaire +1 more source
Deep Learning Integration in Optical Microscopy: Advancements and Applications
It explores the integration of DL into optical microscopy, focusing on key applications including image classification, segmentation, and computational reconstruction. ABSTRACT Optical microscopy is a cornerstone imaging technique in biomedical research, enabling visualization of subcellular structures beyond the resolution limit of the human eye ...
Pottumarthy Venkata Lahari +5 more
wiley +1 more source
Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between
This review deals with many aspects related to the study of phenolic compounds, starting with advances in extraction, detection, and quantification methods, going through bioavailability, bioactivity, and beneficial health properties, and discussing antioxidant and antimicrobial uses and mechanisms.
Marcela de Sá Barreto da Cunha +5 more
wiley +1 more source
Linear Z-line-like alignment of capping protein in obliquely striated muscle of the nematode <i>C. elegans</i> suggests that dense bodies are not equivalent to Z-lines. [PDF]
Ono S +3 more
europepmc +1 more source

