Results 141 to 150 of about 204,221 (349)

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

Characterization of Rosa26-CAG-lox-stop-lox-extracellular-Ruby2-sm-ollas mice.

open access: yes, 2018
(a) Schematic representation of the synthetic construct used for cell surface expression of the ollas antigen: the mouse Tas1R3 signal peptide was attached to a non-fluorescent mRuby-ollas spaghetti monster that was fused to the CD4 transmembrane domain.
Nicholas J. P. Ryba (148103)   +4 more
core   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

open access: yesAdvanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao   +6 more
wiley   +1 more source

Construction of GFP(CAG)89 and GFP(CAG)0 cell lines.

open access: yes, 2014
The GFP(CAG)89 cell line was generated by FLP-mediated site-specific recombination between the FRT sites in plasmid pCAG89 and in the genome of T-REx 293 cells, creating a chromosomal integrant.
Christopher Moye (665754)   +3 more
core   +1 more source

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng   +14 more
wiley   +1 more source

belly-cag

open access: yes, 1972
bellymeaning stomach. Used to mean a pain in the stomach. "He got a pain in his BELLY-CAG" (Cag is sometimes used instead.meaning stomach.DNE-cit JH 6/72Used IUsed IUsed I[see also 'belly kegs'

core  

Flexible IGZO Field‐Effect Transistor Biosensor Platform for Mechanically Stable and Cortisol Detection

open access: yesAdvanced Electronic Materials, EarlyView.
A flexible indium–gallium–zinc oxide field‐effect transistor platform on polyimide is developed for electrostatic cortisol detection. Wafer‐scale fabricated devices exhibit uniform electrical characteristics and maintain stable operation under mechanical bending.
Ngoc Thanh Ho   +3 more
wiley   +1 more source

CAG allele distribution.

open access: yes, 2013
Frequency distribution of CAG alleles in the PCOS cases and control samples (upper panel), and in obese, non-obese and control samples (lower panel).
Mahendra Pratap Singh Negi (468225)   +6 more
core   +1 more source

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