Results 121 to 130 of about 204,221 (349)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Keep Calm and Say Sorry!: The use of Apologies by EFL Teachers in Turkish and English

open access: yesEducational Process: International Journal, 2013
The aim of the study is to investigate apology strategies used by EFL teachers in Turkish and English. For the purpose of the study, a qualitative research was carried out. The study utilized purposeful sampling.
Zeynep Canli, Bekir Canli
doaj   +1 more source

CAG reports once again flag inconsistencies in central irrigation programme

open access: yes, 2018
The Central government decided to table five audit reports by the Comptroller and Auditor General of India (CAG) that were received by government in July, 2018 (one on July 10 and two on July 31) and September, 2018 (one on September 25 and another on ...
Upadhyaya, Himanshu
core  

Intermediate CAG repeats in Huntington's Disease: Analysis of COHORT [PDF]

open access: yes, 2012
Background: There is emerging evidence that clinical and neuro-pathological manifestations of Huntington's disease (HD) may occur in individuals with intermediate length cytosine-adenine-guanine (CAG) repeats (27–35 CAG repeats) in the  ...
Jankovic, Joseph   +5 more
core   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

open access: yesAdvanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang   +6 more
wiley   +1 more source

Correlation between serum testosterone levels and AR CAG repeat length.

open access: yes, 2013
A total of 251 male asymptomatic HBV carriers (AsCs) with normal liver enzyme levels were detected for serum testosterone levels. AR gene alleles were categorized by exon 1 CAG repeat numbers: S-CAG (CAG repeat number 20).
Wen-Ting Tan (503971)   +5 more
core   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

open access: yesAdvanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li   +8 more
wiley   +1 more source

Germ-line CAG repeat instability causes extreme CAG repeat expansion with infantile-onset spinocerebellar ataxia type 2

open access: yes, 2013
The spinocerebellar ataxias (SCA) are a genetically and clinically heterogeneous group of diseases, characterized by dominant inheritance, progressive cerebellar ataxia and diverse extracerebellar symptoms. A subgroup of the ataxias is caused by unstable
Nielsen, Jørgen E   +13 more
core   +1 more source

A Novel Sparse Cellular Labeling System with Tunable Gradients and Long‐Term Stability

open access: yesAdvanced Science, EarlyView.
The Tri‐M (Multi‐recombinase, Multi‐recognition site, and Multi‐nested) sparse cellular labeling system, built upon competitive recombination, integrates transgenic mice with viral injection to achieve tunable and long‐term stable sparse labeling of specific cell types with region selectivity, from sparse populations to individual cells, facilitating ...
Xiaomei Tang   +17 more
wiley   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

open access: yesAdvanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee   +11 more
wiley   +1 more source

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