Results 111 to 120 of about 204,221 (349)

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li   +17 more
wiley   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

open access: yesAdvanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu   +16 more
wiley   +1 more source

Genomic information of children with malignant brain tumors for the prediction of length of hospitalization

open access: yesCancer Communications, 2023
Yichuan Liu   +10 more
doaj   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

open access: yesAdvanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen   +10 more
wiley   +1 more source

Students’ Attitudes Towards Collaborative Tools In A Virtual Learning Environment

open access: yesEducational Process: International Journal, 2015
The purpose of this study is to investigate prep class university students’ attitudes towards collaborative tools used in Moodle. Also it was aimed to find out whether or not there is a difference in students’ attitudes towards traditional and ...
Serife Kalayci, Kim Raymond Humiston
doaj   +1 more source

The Helicobacter pylori cag Pathogenicity Island [PDF]

open access: yes, 2012
The cag pathogenicity island is a well-characterized virulence determinant. It is composed of 32 genes that encode a type IV bacterial secretion system and is linked with a more severe clinical outcome. The following chapters will explore the manipulation of bacterial factors in order to understand their role in gastric mucosal disease.
Jennifer M, Noto, Richard M, Peek
openaire   +2 more sources

MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice

open access: yesPLoS ONE, 2018
In Huntington's disease (HD) patients and in model organisms, messenger RNA transcriptome has been extensively studied; in contrast, comparatively little is known about expression and potential role of microRNAs.
P. Langfelder   +10 more
semanticscholar   +1 more source

Financial development and economic growth: literature survey and empirical evidence from sub-Saharan African countries

open access: yesSouth African Journal of Economic and Management Sciences, 2011
In this paper we review the literature on the finance-growth nexus and investigate the causality between financial development and economic growth in Sub-Saharan Africa for the period 1975-2005.
Songul Kakilli Acaravci   +2 more
doaj   +1 more source

A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington’s disease mice

open access: yesScientific Reports, 2017
Huntington’s disease (HD) is a neurodegenerative disorder whose major symptoms include progressive motor and cognitive dysfunction. Cognitive decline is a critical quality of life concern for HD patients and families.
N. Suelves   +3 more
semanticscholar   +1 more source

CAG nanocomposite synthesis illustration.

open access: yes, 2019
CAG nanocomposite synthesis illustration.
Najihah M. Hashim (6697304)   +6 more
core   +1 more source

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