Results 221 to 230 of about 4,390,669 (264)

SynAtlas: A Safe and Versatile Platform for Rapid Organ‐Scale Tissue Clearing and 3D Atlas Mapping

Advanced Science, EarlyView.
An orthogonal synergy design principle integrates lipid solubilization, protein hydration modulation, and refractive‐index matching within a unified aqueous clearing system. This modular strategy enables rapid, low‐hazard, and broadly compatible tissue clearing while preserving molecular signals, supporting multiscale three‐dimensional imaging across ...
Mei‐Xue Yuan, Xin‐Ya Qin, Ling‐Jie Li, Kai‐Lang Xiao, Meng‐Meng Zhang, Kun‐Qi Chen, Peng Chen, Yu Wang, Chen‐Wei Wang, Nan Zhou, Qing‐Hong Shan   +10 more
wiley   +1 more source

Effect of Rearing System and Season on Herbage Intake, Performance and Meat Nutritional Quality of Growing Rabbits. [PDF]

Animals (Basel)
Bosa L, Dal Bosco A, Mattioli S, Vispi M, Nompleggio L, Bernabucci G, Primi R, Castellini C.   +7 more
europepmc   +1 more source

Pharmacokinetic Tuning Redirects β‐Lapachone From NQO1 Bioactivation to Vimentin‐Targeted Oxidation in Cancer

Advanced Science, EarlyView.
Pharmacokinetic tuning acts as a programmable mechanistic switch for β‐lap. Sustained low‐concentration exposure redirects β‐lap from NQO1 bioactivation to direct oxidation of vimentin, driving disulfide crosslinking, proteasomal overload and ferroptosis.
Lei Dou, Huiqin Liu, Kaixin Wang, Yi Xia, Zhidong Chen, Feng Qian   +5 more
wiley   +1 more source

Finding Mr. Right: Housing Quality Affects Male Mouse Attractiveness to Females, With Implications for Conservation Captive Breeding. [PDF]

Zoo Biol
Anandarajan P, Cai J, Mason G.
europepmc   +1 more source

Hypoxic Preconditioning Restores NK Cell Metabolic Fitness by Attenuating MAPK Signaling to Potentiate Antitumor Immunity in Lung Cancer

Advanced Science, EarlyView.
Solid tumor hypoxia severely compromises natural killer cell function. This study demonstrates that hypoxic preconditioning preserves NK cell antitumor activity by limiting excessive stress ‐MAPK signaling and promoting mitochondrial metabolic fitness.
Dian Zhuang, Xiaoyue Zhu, Na Wang, Qianqian Liu, Lihua Chen, Yanzhuo Ye, Lingrui Shang, Shasha Huang, Cong Ma, Wei Kevin Zhang, Tao Xu, Jiaqi Sun, Huisheng Liu   +12 more
wiley   +1 more source

Impact of Bedding Volume on Cage Microclimate and Behavior in 129SV and Desmin-Knockout (Des-/-) Mice. [PDF]

Animals (Basel)
Minoudi E, Paronis E, Konstantinidis K, Sarikavazis N, Alexakos P, Chaniotis D, Kostavasili I, Kostomitsopoulos N, Voyiatzaki C.   +8 more
europepmc   +1 more source

Roles of Interstitial Albumin in the Subcutaneous Delivery of Therapeutic Peptides

Advanced Science, EarlyView.
A biomimetic extracellular matrix hydrogel platform reveals how interstitial albumin regulates peptide pharmacokinetics after subcutaneous administration. Albumin not only binds peptides but also shows a unique affinity for glycosaminoglycans, thereby reshaping peptide distribution and diffusion.
David Juriga, Anton Norberg, Esther Olaniran Håkansson, Jeroen W. van den Heuvel, Johan Gråsjö, Luke R. Odell, Anna Orlova, Per Hansson   +7 more
wiley   +1 more source

Region-specific neural activity changes and hierarchical instability following social isolation. [PDF]

iScience
Jung T, Kang M, Um S, Noh J, Kim J.
europepmc   +1 more source

A Hierarchical, Model‐Based System for High‐Performance Humanoid Soccer

Advanced Intelligent Systems, EarlyView.
A hierarchical model‐based humanoid soccer system built on ARTEMIS integrates compliant mechanism design, in‐gait kicking, perception, localization, collision‐aware navigation, and behavior planning. Hardware–software codesign aligns mechanical design and control strategy with the requirements of autonomous soccer.
Quanyou Wang, Mingzhang Zhu, Ruochen Hou, Kay Gillespie, Alvin Zhu, Shiqi Wang, Yicheng Wang, Gabriel I. Fernandez, Yeting Liu, Colin Togashi, Hyunwoo Nam, Aditya Navghare, Alex Xu, Taoyuanmin Zhu, Min Sung Ahn, Arturo Flores Alvarez, Justin Quan, Ethan Hong, Dennis W. Hong   +18 more
wiley   +1 more source