Results 51 to 60 of about 992,908 (347)
Geophysical and geochemical controls on the megafaunal community of a high Arctic cold seep [PDF]
Biogeosciences, 2018 Cold-seep megafaunal communities around gas hydrate mounds (pingos) in the western Barents Sea (76° N, 16° E, ∼ 400 m depth) were investigated with high-resolution, geographically referenced images acquired with an ROV and towed camera.
A. Sen +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Communications, 2014 The aim of this paper is to detail the creation of a large tapered roller bearing model with flexible body cages in the Adams program suite for subsequent dynamic analysis and to obtain information about kinematic and dynamic relationships of steel and ...
Robert Kohar, Slavomir Hrcek
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Sea ice and millennial-scale climate variability in the Nordic seas 90 kyr ago to present
Nature Communications, 2016 The response of Arctic sea-ice to rapid climatic change in the past remains uncertain. Here, the authors use biomarkers and microfossils to reconstruct Arctic sea-ice changes over the past 90,000 years, and demonstrate millennial-scale variability.
Ulrike Hoff +4 more
doaj +1 more source
Housing and Management Practices on 33 Pullet Farms in Canada
Animals, 2019 Although Canada is one of the first to provide guidelines on pullet rearing in a new Code of Practice which came into effect in March 2017, little information is available about the housing and management of pullets on Canadian farms.
Nienke van Staaveren +5 more
doaj +1 more source
Bearings use dry self-lubricating cage materials [PDF]
, 1968 Rolling element bearings in spacecraft mechanical systems use solid lubricant composites of polytetrafluoroethylene in the bearing cage which functions as the lubricant reservoir. The cage spaces the rolling elements equally and provides the lubricant at
Anderson, W. J. +2 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Bioengineering, 2023 The success of spinal fusion surgery relies on the precise placement of bone grafts and minimizing scatter. This study aims to optimize cage design and bone substitute filling methods to enhance surgical outcomes.
Cheng-Min Shih +6 more
doaj +1 more source
Thermodynamics of glasses: a first principle computation
, 1998 We propose a first principle computation of the thermodynamics of simple fragile glasses starting from the two body interatomic potential. A replica formulation translates this problem into that of a gas of interacting molecules, each molecule being ...
A. Crisanti +30 more
core +3 more sources