Results 231 to 240 of about 7,222 (340)

Toward more inclusive governance and conservation in the urbanizing Amazon

Conservation Science and Practice, EarlyView.
We propose two paths toward a more inclusive approach to governance and conservation in the urbanizing Amazon: (1) grounding natural resource management programs in local‐level realities and (2) accounting for flows and transformations of place‐based relationships across the rural–urban interface.
Christian J. Rivera, Pamela Montero Alvarez   +1 more
wiley   +1 more source

Disturbed areas promote more parental care and less nesting preference in females of broad-snouted caiman (<i>Caiman latirostris</i>). [PDF]

Anim Welf
Barboza RSL, Correia JMS, Souto A, Schiel N.   +3 more
europepmc   +1 more source

Vonoprazan pharmacokinetics and effects on gastric pH following administration to fed and fasted horses

Equine Veterinary Journal, EarlyView.
Abstract Background Current treatment options for equine gastric ulcer syndrome (EGUS), such as omeprazole—a proton pump inhibitor (PPI)—have notable limitations, including the need for administration on an empty stomach. Potassium‐competitive acid blockers (P‐CABs), such as vonoprazan, are a newer class of acid suppressants that offer several ...
Camilo J. Morales, Benjamin W. Sykes, Daniel S. McKemie, Philip H. Kass, Heather K. Knych   +4 more
wiley   +1 more source

How Happy Do These Animals Look? Exploring Factors Influencing Children's Perceptions of Animal Welfare at the Zoo. [PDF]

Animals (Basel)
Vera-Concha MI, Rojas M, Cartes D, Ceballos MC, Villarroel MC, Pérez M, Venegas V, Briceño C, Calderón-Amor J, Luna D.   +9 more
europepmc   +1 more source

RNF13 is a previously undescribed interactor of iduronate 2‐sulfatase that modifies its glycosylation and maturation

The FEBS Journal, EarlyView.
Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana, Antoine Y. Bouchard, Audrey M. Sénécal, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

The complete mitochondrial genome of <i>Brevimulticaecum sinensis</i> (Nematoda: Heterocheilidae), the first representative of the genus <i>Brevimulticaecum</i>. [PDF]

Mitochondrial DNA B Resour
Zhao J, Marisa T, Tu G, Kuris A, Wu X.
europepmc   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source

A Survey of DNA Damage in American Alligators (Alligator mississippiensis) in Florida. [PDF]

Environ Mol Mutagen
Lu H, Meaza I, Wise RM, Wise JTF, Diven SS, Croom-Pérez TJ, Toyoda JH, Wise JP.   +7 more
europepmc   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

Hypoxia‐preconditioned adipose‐derived mesenchymal stem cells‐derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5‐mediated inactivation of TLR4/NF‐κB/NLRP3 inflammatory signaling

Journal of Diabetes Investigation, EarlyView.
In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian, Xianxi Meng, Bairong Fang, Li Pi   +3 more
wiley   +1 more source