Results 241 to 250 of about 14,518 (334)
PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier +9 more
wiley +1 more source
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade +7 more
wiley +1 more source
Disturbed areas promote more parental care and less nesting preference in females of broad-snouted caiman (<i>Caiman latirostris</i>). [PDF]
Barboza RSL +3 more
europepmc +1 more source
Integrating camera-trap photo-identification into non-invasive monitoring of Caiman latirostris
Sofía E. Pierini +7 more
openalex +1 more source
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić +25 more
wiley +1 more source
Occurrence dataset of reptiles and amphibians from two old-growth forest localities along the Las Piedras River, Tambopata Province, Peru. [PDF]
Crnobrna B +4 more
europepmc +1 more source
Receptor‐induced Kv7/M‐current suppression increases neuronal activity and contributes to pathology of several conditions. A new class of Kv7 modulators identified in this study attenuates M‐current suppression and shows therapeutic effects. Abstract Background and Purpose Neuronal Kv7 channels generate low voltage–gated potassium currents known as the
Young Woo Kim +5 more
wiley +1 more source
Background and Purpose Maternal hypoxia is a recognised risk factor for neurodevelopmental disorders in offspring. Although rodent models of hypoxia have been reported, the detailed pathogenesis of maternal hypoxia‐induced neurodevelopmental disorders remains unclear.
Kentaro Tokudome +6 more
wiley +1 more source
Analyzing the Life History of Caimans: The Growth Dynamics of Caiman latirostris From an Osteohistological Approach. [PDF]
Pereyra ME +3 more
europepmc +1 more source

