Results 251 to 260 of about 7,222 (340)

Effects of Oral Single‐Dose Empagliflozin on Urinary Glucose, Serum β‐Hydroxybutyrate, and Plasma Empagliflozin Concentrations in Healthy Adult Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Empagliflozin is a sodium‐glucose cotransporter‐2 inhibitor used for treating humans with heart failure, among other conditions. This drug could have applications in veterinary cardiology, but whether empagliflozin has biological effects in dogs when administered at dosages approximating human therapeutic dosages is unknown.
Andrea D. Plá Gutierrez, M. Lynne O'Sullivan, Etienne Côté, Sandra McConkey, Butch KuKanich, Stephanie E. Martinez   +5 more
wiley   +1 more source

PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness, photostability and multiplexing capabilities. [PDF]

Nat Methods
Fink R, Imai S, Gockel N, Lauer G, Renken K, Wietek J, Lamothe-Molina PJ, Fuhrmann F, Mittag M, Ziebarth T, Canziani A, Kubitschke M, Kistmacher V, Kretschmer A, Sebastian E, Ottens J, Schmitz D, Terai T, Gründemann J, Hassan SI, Patriarchi T, Reiner A, Fuhrmann M, Campbell RE, Masseck OA.   +24 more
europepmc   +1 more source

In Salmonella Typhimurium, YiiD Modulates cAMP Levels in Lag Phase During Growth on Succinate

Molecular Microbiology, EarlyView.
The YiiD enzyme, found by others to perform a redundant role in fatty acid biosynthesis, is found to be unexpectedly required for the early increase in cAMP in lag phase during growth on succinate. This intriguing finding suggests a mechanistic link may exist between fatty acid biosynthesis and catabolite repression. ABSTRACT In Salmonella Typhimurium (
John A. Ciemniecki, Jessica L. Will, Jorge C. Escalante‐Semerena   +2 more
wiley   +1 more source

The velar chord and dynamic integration of the gular valve in crocodylians. [PDF]

Anat Rec (Hoboken)
Young BA, Cramberg M, Young OG.
europepmc   +1 more source

Nitric Oxide Tunes Secreted Metabolite Bioactivity

Molecular Microbiology, EarlyView.
Pseudomonas aeruginosa produces phenazine metabolites that can react with nitric oxide (·NO) to form nitrosylated compounds. The formation of these metabolites results in rapid loss in P. aeruginosa viability and diminishes phenazine antimicrobial activity against other organisms, including Staphylococcus aureus. ABSTRACT The radical nitric oxide (·NO)
Zachery R. Lonergan, Sarah L. Weisflog, Matthew Scurria, Jinyang Li, Korbinian Thalhammer, Osvaldo Gutierrez, Stuart J. Conway, Dianne K. Newman   +7 more
wiley   +1 more source

Experience and behavior modulate piriform cortex odor representation in freely moving mice. [PDF]

iScience
Chapman IF, Raymond MA, Fletcher ML.
europepmc   +1 more source

Evaluation of HSYA and Carthamin Accumulation in Safflower (Carthamus tinctorius L.) Induced by Chemical Mutagens (EMS and SA) in M1 and M2 Generations

Plant Breeding, EarlyView.
ABSTRACT Historically cultivated for medicinal and dyeing purposes, safflower (Carthamus tinctorius L.) saw a shift towards widespread oilseed production after the 1920s due to the growing importance of oils. However, there is a renewed interest in its medicinal and dyeing properties today.
Tansu Uskutoglu, Nurullah Kartaloglu, Belgin Cosge Senkal   +2 more
wiley   +1 more source

Antioxidants Differentially Regulate Non‐Photochemical Quenching

Plant, Cell &Environment, EarlyView.
ABSTRACT Non‐photochemical quenching (NPQ) dissipates excess light energy as heat, limiting reactive oxygen species production during photosynthesis. Exogenous antioxidants are widely reported to improve plant performance under stress, yet their impacts on NPQ are inconsistent across studies, complicating mechanistic interpretation.
Aline de Rodrigues de Queiroz, Jeremy H. Brown, Nicole R. Buan, Julie M. Stone, Katarzyna Glowacka, Rebecca L. Roston   +5 more
wiley   +1 more source

An end-to-end recurrent compressed sensing method to denoise, detect and demix calcium imaging data. [PDF]

Nat Mach Intell
Zhang K, Tang S, Zhu V, Barchini M, Yang W.   +4 more
europepmc   +1 more source

Oxidative stress in honey bees (Apis mellifera) and small carpenter bees (Ceratina calcarata) across different landscapes

Physiological Entomology, EarlyView.
First comparative study in oxidative stress between wild bees and managed bees. Bees collected from organic landscapes exhibited the lowest OX levels. Pesticide profiles were different among landscapes. Abstract Oxidative stress (OX) is a state of imbalance between antioxidants and reactive oxygen species, which are the byproducts of oxidative ...
Keiana Briscoe, Mia Byarlay, Rameshwor Pudasaini, Reed Johnson, Sandra Rehan, Hongmei Li‐Byarlay   +5 more
wiley   +1 more source