Results 261 to 270 of about 14,518 (334)

Polling the Public to Select Flagship Species for Tourism and Conservation-A 'Big Five' for the Peruvian Amazon? [PDF]

Ecol Evol
Recharte M, Lee PC, Vick SJ, Bowler M.
europepmc   +1 more source

Coenzyme A mitigates cystine‐deprivation‐induced ferroptosis by suppressing the iron‐starvation response

The FEBS Journal, EarlyView.
Cystine (Cys2) deprivation in pancreatic cancer cells induces oxidative stress that destabilizes cytosolic iron–sulfur cluster (ISC) proteins, triggering an iron‐regulatory protein (IRP)‐mediated iron‐starvation response (ISR). This leads to increased iron uptake (via TFRC), an expanded labile iron pool, and ferroptosis.
Mingjun Tan, Yunzhan Li, Lei Sang, Min Wang, Qin Li, Zekun Li, Dongxiao Sun, Xiuchao Wang, Shengyu Yang   +8 more
wiley   +1 more source

Laparoscopic-assisted ovariohysterectomy for pyometra with concurrent endometriosis in a captive cheetah (<i>Acinonyx jubatus</i>): A case report. [PDF]

Open Vet J
Guadalupi M, Orlandi M, Laricchiuta P, Abramo F, Piemontese C, Lacitignola L.   +5 more
europepmc   +1 more source

Schneider's smooth-fronted caiman Paleosuchus trigonatus.

, 2010
W. E. MAGNUSSON, Z. M. da S. CAMPOS
openalex   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source

Neural coding of choice and outcome are modulated by uncertainty in orbitofrontal but not secondary motor cortex. [PDF]

Nat Commun
Romero-Sosa JL, Yeghikian A, Wikenheiser AM, Blair HT, Izquierdo A.   +4 more
europepmc   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

The velar chord and dynamic integration of the gular valve in crocodylians. [PDF]

Anat Rec (Hoboken)
Young BA, Cramberg M, Young OG.
europepmc   +1 more source

TREM‐1 Blockade Inhibits Inflammasome Activation and Pyroptosis: Novel Insights on the Role of TREM‐1 and Syk in Monosodium Urate Crystal‐Induced Inflammation

Immunology, EarlyView.
Schematic overview of the roles triggering receptor expressed on myeloid cells‐1 (TREM‐1) plays in monosodium urate (MSU) crystal‐induced inflammasome activation and IL‐1β secretion in gout arthritis. The present study provides novel data suggesting that blockade of TREM‐1 by LP17 attenuates MSU‐crystal‐induced inflammation through inhibition of ...
Yair Molad, Irina Lagovsky, Vitaly Kliminski   +2 more
wiley   +1 more source

Evaluating the ergonomic aspects of laparoscopic energy devices: combination of a survey and a kinesiologic experiment. [PDF]

Surg Endosc
Sohn HJ, Song J, Choi YS, Han Y, Kwon W, Park J, Jang JY.   +6 more
europepmc   +1 more source