Results 261 to 270 of about 15,530 (328)

TREM‐1 Blockade Inhibits Inflammasome Activation and Pyroptosis: Novel Insights on the Role of TREM‐1 and Syk in Monosodium Urate Crystal‐Induced Inflammation

open access: yesImmunology, EarlyView.
Schematic overview of the roles triggering receptor expressed on myeloid cells‐1 (TREM‐1) plays in monosodium urate (MSU) crystal‐induced inflammasome activation and IL‐1β secretion in gout arthritis. The present study provides novel data suggesting that blockade of TREM‐1 by LP17 attenuates MSU‐crystal‐induced inflammation through inhibition of ...
Yair Molad   +2 more
wiley   +1 more source

NeuroART: Real-Time Analysis and Targeting of Neuronal Population Activity during Calcium Imaging for Informed Closed-Loop Experiments. [PDF]

open access: yeseNeuro
Bowen Z   +7 more
europepmc   +1 more source

Optogenetic interrogation of the zebrafish lateral line reveals brain-wide neural circuits involved in pattern separation. [PDF]

open access: yesiScience
Velez-Angel N   +7 more
europepmc   +1 more source

Quadrate orientation and joint reaction force underwent correlated evolution during suchian evolution

open access: yesJournal of Anatomy, EarlyView.
The quadrate is the cranial bone of the nonmammalian jaw joint. The quadrate has long been hypothesized to mirror the direction of joint reaction forces (JRF) during feeding. This study uses 3D biomechanical modeling to reveal a striking evolutionary link between quadrate orientation and JRF direction, unlocking new insights into the dynamic forces ...
Kaleb C. Sellers   +4 more
wiley   +1 more source

Comparative endocranial anatomy in the crocodylians Leidyosuchus canadensis and Stangerochampsa mccabei from the upper Cretaceous of Alberta, Canada

open access: yesJournal of Anatomy, EarlyView.
Leidyosuchus canadensis and Stangerochampsa mccabei share endocranial features such as posterior projection of a neurovascular canal in the maxilla and a paratympanic sinus system most similar to those of small‐bodied and young extant crocodylians, suggesting that these pedomorphic features may reflect the ancestral crocodylian condition.
G. Donzé   +4 more
wiley   +1 more source

Pharmacokinetic Parameters of Oral Firocoxib, Oral Meloxicam, and Transdermal Flunixin in Meat Type Goats

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The objective of this study was to determine and compare the pharmacokinetics of oral firocoxib, oral meloxicam, and transdermal flunixin (TD) in 44 adult, male castrated, crossbred goats. Pharmacokinetic (PK) analysis was performed for each goat in each phase using non‐compartmental methods with descriptive statistics reported.
Mikaela M. Weeder   +11 more
wiley   +1 more source

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