Results 61 to 70 of about 15,530 (328)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Alligator mississippiensis [PDF]

, 1994
Number of Pages: 14Integrative BiologyGeological ...
Ernst, Carl H., Ross, Charles A.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Variation in diet of hatchlings, juveniles and sub-adults of Caiman crocodilus chiapasius in La Encrucijada, Chiapas, Mexico

Revista Mexicana de Biodiversidad, 2020
Little is known about the diet of the Chiapas spectacled caiman, Caiman crocodilus chiapasius (Bocourt, 1876), in the southern coast of Mexico. Herein, we analyzed the stomach content of 44 caimans divided into 3 size classes in La Encrucijada, Chiapas,
Gerardo J. Soria-Ortiz, Pierre Charruau, Víctor Hugo Reynoso   +2 more
doaj   +1 more source

Comparison of Two Radiofrequency Vessel-Sealing Device for Laparoscopic Ovariectomy in African Lionesses (Panthera Leo)

Animals, 2022
To evaluate two vessel-sealing devices with different jaw lengths for dissecting ovaries in adult obese African lionesses undergoing laparoscopic ovariectomy. Twelve lionesses (n = 12) were recruited.
Luca Lacitignola, Pietro Laricchiuta, Marta Guadalupi, Marzia Stabile, Annalaura Scardia, Mario Cinone, Francesco Staffieri   +6 more
doaj   +1 more source

Behavioral thermoregulation in the spectacled caiman (Caiman sclerops) [PDF]

Behavior Research Methods & Instrumentation, 1976
This report describes an operant conditioning technique for studying crocodilians. As experimental subjects, crocodilians present some special problems. For example, their size limits direct handling. Further, because they may go for prolonged periods without eating, food probably is not an effective reinforcer.
openaire   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Better use of caiman yacare carcass and physical-chemical characterization of mechanically separated meat

Ciência Rural
: The captive breeding of the Pantanal caiman (Caiman yacare) offers great potential for the full use of all the component parts of the animal.
Gilmar Borges de Paiva, Elisa Rafaela Bonádio Bellucci, Marco Antônio Trindade, Javier Teles Romero, Andrea Carla da Silva Barretto   +4 more
doaj   +1 more source

Predation of the giant Miocene caiman Purussaurus on a mylodontid ground sloth in the wetlands of proto-Amazonia

Biology Letters, 2020
Thirteen million years ago in South America, the Pebas Mega-Wetland System sheltered multi-taxon crocodylian assemblages, with the giant caiman Purussaurus as the top predator.
F. Pujos, R. Salas‐Gismondi
semanticscholar   +1 more source

“Intracascaral space” an eggshell structure of Caiman latirostris eggs

Scientific Reports, 2021
In recent decades, eggshells of eggs from large-bodied reptiles have been studied by many researchers, to describe the eggshell, to compare them to extinct lineages that once inhabited our planet and also to understand how the egg provides the embryo ...
Mila V. Piazza, M. S. Fernández, P. M. Leiva, C. Piña, M. Simoncini   +4 more
semanticscholar   +1 more source