Results 81 to 90 of about 30,051 (262)

Unwrapping the role of WRAP53β in DNA damage response [PDF]

open access: yes, 2016
WRAP53β is a WD40 domain protein with multifaceted capabilities in several biological processes in different cellular compartments. This includes transportation of the Survival of motor neuron (SMN) complex, small Cajal body-specific (sca) RNAs and the ...
Rassoolzadeh, Hanif
core   +1 more source

Rationale of New Grading System: Central Compartment Atopic Disease

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Central compartment atopic disease (CCAD) has recently been recognized as a distinct phenotype within the spectrum of type 2–dominant chronic rhinosinusitis (CRS). Although international guidelines highlight polypoid changes in the central nasal cavity, standardized diagnostic and classification criteria are still lacking.
Ramón Moreno‐Luna   +11 more
wiley   +1 more source

Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]

open access: yes, 2016
Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E.   +5 more
core   +1 more source

FLASH is an essential component of Cajal bodies [PDF]

open access: yesProceedings of the National Academy of Sciences, 2006
Cajal bodies are small nuclear organelles with a number of nuclear functions. Here we show that FLICE-associated huge protein (FLASH), originally described as a component of the apoptosis signaling pathway, is mainly localized in Cajal bodies and is essential for their structure.
Barcaroli D.   +12 more
openaire   +3 more sources

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

open access: yesBMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim   +5 more
wiley   +1 more source

A Viral Suppressor of RNA Silencing May Be Targeting a Plant Defence Pathway Involving Fibrillarin

open access: yesPlants, 2022
To establish productive infections, viruses must be able both to subdue the host metabolism for their own benefit and to counteract host defences. This frequently results in the establishment of viral–host protein–protein interactions that may have ...
Miryam Pérez-Cañamás   +2 more
doaj   +1 more source

WRAP53 Unwrapped; Roles in Nuclear Architecture and Cancer [PDF]

open access: yes, 2011
WRAP53 is a gene of multiple functions; it encodes for a natural antisense transcript that regulates the actions of the tumour suppressor p53, and it gives rise to a protein with oncogenic properties that is important for Cajal body formation and ...
Mahmoudi, Salah
core   +1 more source

Bottom‐up Strategies for Generating Polymer Protocells That Mimic Cellular Communication

open access: yesChemistry – A European Journal, EarlyView.
This review focuses on polymeric protocells produced using a bottom‐up approach. Polymer‐based assemblies guarantee stability and designability by adjusting the properties of the amphiphilic copolymers used. The review covers protocell architectures, production, and their intra‐ and intercellular communication mechanisms.
Gloria Saorin   +3 more
wiley   +1 more source

Altered dynamics of scaRNA2 and scaRNA9 in response to stress correlates with disrupted nuclear organization

open access: yesBiology Open, 2018
Small Cajal body-specific RNAs (scaRNAs) are part of small Cajal body-specific ribonucleoproteins (scaRNPs) that modify small nuclear RNA (snRNA) in Cajal bodies (CBs).
Madelyn K. Logan   +2 more
doaj   +1 more source

Signals controlling Cajal body assembly and function [PDF]

open access: yesThe International Journal of Biochemistry & Cell Biology, 2013
Cajal bodies (CBs) are subnuclear domains that participate in the biogenesis of small nuclear ribonucleoproteins (snRNPs) and telomerase. CBs are found in cells with high splicing demands, such as neuronal and cancer cells. The purpose of this review is to highlight what is known about the signals that impact the formation and activity of CBs ...
openaire   +2 more sources

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