Results 1 to 10 of about 51,957 (163)
Cell Reports, 2016 The nucleolus is the site of rRNA gene transcription, rRNA processing, and ribosome biogenesis. However, the nucleolus also plays additional roles in the cell. We isolated nucleoli using fluorescence-activated cell sorting (FACS) and identified nucleolus-
Frédéric Pontvianne +2 more
exaly +3 more sources
Nature Communications, 2023 Here the authors developed a nucleolus Hi-C technique (nHi-C) for enriching nucleolus-associated interactions, and revealed specific heterochromatin interaction patterns within and around nucleoli in human cells at high resolution.
Haowei Meng, Yong Cao, Lumeng Jia
exaly +2 more sources
Genome Organization in and around the Nucleolus
Cells, 2019 The nucleolus is the largest substructure in the nucleus, where ribosome biogenesis takes place, and forms around the nucleolar organizer regions (NORs) that comprise ribosomal RNA (rRNA) genes.
Raffaella Santoro, Santoro Raffaella
exaly +3 more sources
Therapeutic Approaches Targeting Nucleolus in Cancer
Cells, 2019 The nucleolus is a distinct sub-cellular compartment structure in the nucleus. First observed more than 200 years ago, the nucleolus is detectable by microscopy in eukaryotic cells and visible during the interphase as a sub-nuclear structure immersed in ...
Pietro Carotenuto, Gaetano Palma
exaly +3 more sources
Mètode Science Studies Journal: Annual Review, 2021 Space exploration will require life support systems, in which plants can provide nutrients, oxygen, moisture, and psychological well-being and eliminate wastes. In alien environments, plants must adapt to a different gravity force, even the zero gravity
F. Javier Medina
doaj +1 more source
iScience, 2022 Summary: Discovering the adaptation mechanisms of plants to the space environment is essential for supporting human space exploration. Transcriptomic analyses allow the identification of adaptation response pathways by detecting changes in gene ...
Aránzazu Manzano +3 more
doaj +1 more source
Cold Spring Harbor Perspectives in Biology, 2010 When cells are observed by phase contrast microscopy, nucleoli are among the most conspicuous structures. The nucleolus was formally described between 1835 and 1839, but it was another century before it was discovered to be associated with a specific chromosomal locus, thus defining it as a cytogenetic entity. Nucleoli were first isolated in the 1950s,
B R, SESHACHAR, K V, SRINATH
openaire +4 more sources
Cells, 2021 Due to their exceptional simplicity of organization, viruses rely on the resources, molecular mechanisms, macromolecular complexes, regulatory pathways, and functional compartments of the host cell for an effective infection process.
Olga V. Iarovaia +3 more
doaj +1 more source
Current Opinion in Cell Biology, 1994 The transcriptionally active rRNA genes have the remarkable ability to organize and integrate the biochemical pathway of ribosome production into a structural framework, the nucleolus. The past year has seen numerous advances in our understanding of the relationships between nucleolar substructures, the site of ribosomal RNA (rRNA) gene transcription ...
Scheer, Ulrich, Weisenberger, Dieter
openaire +2 more sources
Fibrillarin-GFP Facilitates the Identification of Meiotic Competent Oocytes
Frontiers in Cell and Developmental Biology, 2021 The nucleolus undergoes significant functional changes and plays important roles during mammalian oocyte meiotic maturation. Fibrillarin (FBL) is the component of nucleolar small nuclear ribonucleoprotein (snRNP) particle and localizes to the dense ...
Ting Wang, Ting Wang, Jie Na
doaj +1 more source