Results 1 to 10 of about 53,096 (163)
Nature Communications, 2023 Here the authors developed a nucleolus Hi-C technique (nHi-C) for enriching nucleolus-associated interactions, and revealed specific heterochromatin interaction patterns within and around nucleoli in human cells at high resolution.
Yingping Hou, Haowei Meng, Cheng Li
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Mechanobiology of the Nucleolus. [PDF]
Biol CellABSTRACT Ribosome biogenesis is an essential and energy‐demanding process required to maintain cellular proteostasis. The nucleolus, which orchestrates this vital process, assembles as a nuclear condensate and exhibits remarkable plasticity in its structure, function, and protein composition.
Shetty Y, Dolega ME.
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Cell Reports, 2016 The nucleolus is the site of rRNA gene transcription, rRNA processing, and ribosome biogenesis. However, the nucleolus also plays additional roles in the cell. We isolated nucleoli using fluorescence-activated cell sorting (FACS) and identified nucleolus-
Craig Pikaard +2 more
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Mètode Science Studies Journal: Annual Review, 2021 Space exploration will require life support systems, in which plants can provide nutrients, oxygen, moisture, and psychological well-being and eliminate wastes. In alien environments, plants must adapt to a different gravity force, even the zero gravity
F. Javier Medina
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iScience, 2022 Summary: Discovering the adaptation mechanisms of plants to the space environment is essential for supporting human space exploration. Transcriptomic analyses allow the identification of adaptation response pathways by detecting changes in gene ...
Aránzazu Manzano +3 more
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Cold Spring Harbor Perspectives in Biology, 2010 When cells are observed by phase contrast microscopy, nucleoli are among the most conspicuous structures. The nucleolus was formally described between 1835 and 1839, but it was another century before it was discovered to be associated with a specific chromosomal locus, thus defining it as a cytogenetic entity. Nucleoli were first isolated in the 1950s,
B R, SESHACHAR, K V, SRINATH
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Cells, 2021 Due to their exceptional simplicity of organization, viruses rely on the resources, molecular mechanisms, macromolecular complexes, regulatory pathways, and functional compartments of the host cell for an effective infection process.
Olga V. Iarovaia +3 more
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Fibrillarin-GFP Facilitates the Identification of Meiotic Competent Oocytes
Frontiers in Cell and Developmental Biology, 2021 The nucleolus undergoes significant functional changes and plays important roles during mammalian oocyte meiotic maturation. Fibrillarin (FBL) is the component of nucleolar small nuclear ribonucleoprotein (snRNP) particle and localizes to the dense ...
Ting Wang, Ting Wang, Jie Na
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Current Opinion in Cell Biology, 1994 The transcriptionally active rRNA genes have the remarkable ability to organize and integrate the biochemical pathway of ribosome production into a structural framework, the nucleolus. The past year has seen numerous advances in our understanding of the relationships between nucleolar substructures, the site of ribosomal RNA (rRNA) gene transcription ...
Scheer, Ulrich, Weisenberger, Dieter
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Beyond ribosome biogenesis: noncoding nucleolar RNAs in physiology and tumor biology
Nucleus, 2023 The nucleolus, the largest subcompartment of the nucleus, stands out from the nucleoplasm due to its exceptionally high local RNA and low DNA concentrations.
Nuray Böğürcü-Seidel +3 more
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