Results 11 to 20 of about 51,957 (163)

Beyond ribosome biogenesis: noncoding nucleolar RNAs in physiology and tumor biology

open access: yesNucleus, 2023
The nucleolus, the largest subcompartment of the nucleus, stands out from the nucleoplasm due to its exceptionally high local RNA and low DNA concentrations.
Nuray Böğürcü-Seidel   +3 more
doaj   +1 more source

The structure of the mitotic spindle and nucleolus during mitosis in the amebo-flagellate Naegleria. [PDF]

open access: yesPLoS ONE, 2012
Mitosis in the amebo-flagellate Naegleria pringsheimi is acentrosomal and closed (the nuclear membrane does not break down). The large central nucleolus, which occupies about 20% of the nuclear volume, persists throughout the cell cycle.
Charles J Walsh
doaj   +1 more source

Matrix Metalloprotease-7 Mediates Nucleolar Assembly and Intra-nucleolar Cleaving p53 in Gefitinib-Resistant Cancer Stem Cells

open access: yesiScience, 2020
Summary: The enlarged distinct bulky-ball-like nucleolus matrix assembly is observed in most cancer stem cells (CSCs); however, the underlying mechanism is largely unknown.
Wei-Hsuan Yu   +8 more
doaj   +1 more source

The nucleolus functions as the compartment for histone H2B protein degradation

open access: yesiScience, 2021
Summary: Histones are main components of chromatin, and the protein levels of histones significantly affect chromatin assembly. However, how histone protein levels are regulated, especially whether and how histones are degraded, is largely unclear. Here,
Yanping Liu   +12 more
doaj   +1 more source

Nucleolar Organization and Functions in Health and Disease

open access: yesCells, 2020
The nucleolus is a prominent, membraneless compartment found within the nucleus of eukaryotic cells. It forms around ribosomal RNA (rRNA) genes, where it coordinates the transcription, processing, and packaging of rRNA to produce ribosomal subunits ...
Ursula Stochaj, Stephanie C. Weber
doaj   +1 more source

Distinct dynamics of the nucleolus in response to nutrient availability and during development in the rice blast fungus

open access: yesmBio, 2023
The nucleolus has emerged as a central hub for nuclear functions in eukaryotes. Studies in mammals and the model yeast Saccharomyces cerevisiae showed that the nucleolus is pivotal to nuclear functions other than ribosome biogenesis.
Eunbyeol Cho   +3 more
doaj   +1 more source

On the Locus of the Nucleolus [PDF]

open access: yes, 1994
In this paper we prove some properties of the locus of the nucleolus of a set C that can be the core of a cooperative game. We show that there are two subsets of C, the kernel and the least core, only dependent on the set C that contain this locus. From this fact we derive that for a set C which is the core of convex game the locus consists of one ...
Potters, J.A.M., Tijs, S.H.
openaire   +3 more sources

Nucleolus and chromatin [PDF]

open access: yesHistochemistry and Cell Biology, 2018
The nucleolus as site of ribosome biogenesis holds a pivotal role in cell metabolism. It is composed of ribosomal DNA (rDNA), which is present as tandem arrays located in nucleolus organizer regions (NORs). In interphase cells, rDNA can be found inside and adjacent to nucleoli and the location is indicative for transcriptional activity of ribosomal ...
Christian Schöfer, Klara Weipoltshammer
openaire   +2 more sources

Nucleolar Proteome Analysis and Proteasomal Activity Assays Reveal a Link between Nucleolus and 26S Proteasome in A. thaliana

open access: yesFrontiers in Plant Science, 2017
In all eukaryotic cells, the nucleolus is functionally and structurally linked to rRNA synthesis and ribosome biogenesis. This compartment contains as well factors involved in other cellular activities, but the functional interconnection between non ...
Charlotte Montacié   +17 more
doaj   +1 more source

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