Results 1 to 10 of about 50,397 (164)

Assemblies of d-Peptides for Targeting Cell Nucleolus. [PDF]

open access: yesBioconjug Chem, 2019
Selectively targeting cell nucleolus remains a challenge. Here we report the first case that D-peptides form membraneless molecular condensates with RNA for targeting cell nucleolus. A D-peptide derivative, enriched with lysine and hydrophobic residues, self-assembles to form nanoparticles, which enter cells through clathrin dependent endocytosis ...
Wang H, Feng Z, Tan W, Xu B.
europepmc   +4 more sources

The nucleolus: a paradigm for cell proliferation and aging [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 1999
The nucleolus is the cellular site of ribosome biosynthesis. At this site, active ribosomal DNA (rDNA) genes are rapidly transcribed by RNA polymerase I (pol I) molecules.
Comai L.
doaj   +5 more sources

Nucleolus and Nucleolar Stress: From Cell Fate Decision to Disease Development

open access: yesCells, 2022
Besides the canonical function in ribosome biogenesis, there have been significant recent advances towards the fascinating roles of the nucleolus in stress response, cell destiny decision and disease progression.
Lu Hua   +3 more
doaj   +3 more sources

The Nucleolus and Parachromatin of the Ascites Tumor Cell [PDF]

open access: yesJournal of Cell Biology, 1957
1. A method is described for distinguishing the ribonucleoproteins of the nucleolus and parachromatin of ascitic tumor cells of the mouse. 2. In these cells the transfer of ribonucleoprotein from the nucleus to the cytoplasm can occur in two ways.
R Love
exaly   +3 more sources

Plant cell nucleolus as a hot spot for iron. [PDF]

open access: yesJ Biol Chem, 2011
Many central metabolic processes require iron as a cofactor and take place in specific subcellular compartments such as the mitochondrion or the chloroplast. Proper iron allocation in the different organelles is thus critical to maintain cell function and integrity.
Roschzttardtz H   +6 more
europepmc   +6 more sources

ULTRASTRUCTURE OF THE NUCLEOLUS DURING THE CHINESE HAMSTER CELL CYCLE [PDF]

open access: yesJournal of Cell Biology, 1971
Changes in the structure of the nucleolus during the cell cycle of the Chinese hamster cell in vitro were studied. Quantitative electron microscopic techniques were used to establish the size and volume changes in nucleolar structures. In mitosis, nucleolar remnants, "persistent nucleoli," consisting predominantly of ribosome-like granular material ...
J S, Noel   +3 more
exaly   +3 more sources

Space explorers need to be space farmers: What we know and what we need to know about plant growth in space

open access: yesMètode Science Studies Journal: Annual Review, 2021
Space exploration will require life support systems, in which plants can provide nutrients, oxygen, moisture, and psychological well-being and eliminate wastes. In alien environments, plants must adapt to a different gravity force, even the zero gravity
F. Javier Medina
doaj   +1 more source

Recent transcriptomic studies to elucidate the plant adaptive response to spaceflight and to simulated space environments

open access: yesiScience, 2022
Summary: Discovering the adaptation mechanisms of plants to the space environment is essential for supporting human space exploration. Transcriptomic analyses allow the identification of adaptation response pathways by detecting changes in gene ...
Aránzazu Manzano   +3 more
doaj   +1 more source

Manipulation of Cellular Processes via Nucleolus Hijaking in the Course of Viral Infection in Mammals

open access: yesCells, 2021
Due to their exceptional simplicity of organization, viruses rely on the resources, molecular mechanisms, macromolecular complexes, regulatory pathways, and functional compartments of the host cell for an effective infection process.
Olga V. Iarovaia   +3 more
doaj   +1 more source

Developmental regulation of nucleolus size during Drosophila eye differentiation. [PDF]

open access: yesPLoS ONE, 2013
When cell cycle withdrawal accompanies terminal differentiation, biosynthesis and cellular growth are likely to change also. In this study, nucleolus size was monitored during cell fate specification in the Drosophila eye imaginal disc using fibrillarin ...
Nicholas E Baker
doaj   +1 more source

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