Results 1 to 10 of about 52,621 (199)
Assemblies of d-Peptides for Targeting Cell Nucleolus. [PDF]
Bioconjug Chem, 2019 Selectively targeting the cell nucleolus remains a challenge. Here, we report the first case in which d-peptides form membraneless molecular condensates with RNA for targeting cell nucleolus. A d-peptide derivative, enriched with lysine and hydrophobic residues, self-assembles to form nanoparticles, which enter cells through clathrin-dependent ...
Wang H, Feng Z, Tan W, Xu B.
europepmc +7 more sources
The nucleolus: a paradigm for cell proliferation and aging [PDF]
Brazilian Journal of Medical and Biological Research, 1999 The nucleolus is the cellular site of ribosome biosynthesis. At this site, active ribosomal DNA (rDNA) genes are rapidly transcribed by RNA polymerase I (pol I) molecules.
Comai L.
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Nucleolus and Nucleolar Stress: From Cell Fate Decision to Disease Development
Cells, 2022 Besides the canonical function in ribosome biogenesis, there have been significant recent advances towards the fascinating roles of the nucleolus in stress response, cell destiny decision and disease progression.
Lu Hua +3 more
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Cells, 2021 Due to their exceptional simplicity of organization, viruses rely on the resources, molecular mechanisms, macromolecular complexes, regulatory pathways, and functional compartments of the host cell for an effective infection process.
Olga V. Iarovaia +3 more
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Mètode Science Studies Journal: Annual Review, 2021 Space exploration will require life support systems, in which plants can provide nutrients, oxygen, moisture, and psychological well-being and eliminate wastes. In alien environments, plants must adapt to a different gravity force, even the zero gravity
F. Javier Medina
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iScience, 2022 Summary: Discovering the adaptation mechanisms of plants to the space environment is essential for supporting human space exploration. Transcriptomic analyses allow the identification of adaptation response pathways by detecting changes in gene ...
Aránzazu Manzano +3 more
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Developmental regulation of nucleolus size during Drosophila eye differentiation. [PDF]
PLoS ONE, 2013 When cell cycle withdrawal accompanies terminal differentiation, biosynthesis and cellular growth are likely to change also. In this study, nucleolus size was monitored during cell fate specification in the Drosophila eye imaginal disc using fibrillarin ...
Nicholas E Baker
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PLoS Pathogens, 2022 Nucleoli are membrane-less structures located within the nucleus and are known to be involved in many cellular functions, including stress response and cell cycle regulation. Besides, many viruses can employ the nucleolus or nucleolar proteins to promote
Sereina O Sutter +8 more
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rRNA transcription is integral to phase separation and maintenance of nucleolar structure.
PLoS Genetics, 2023 Transcription of ribosomal RNA (rRNA) by RNA Polymerase (Pol) I in the nucleolus is necessary for ribosome biogenesis, which is intimately tied to cell growth and proliferation.
Soma Dash +13 more
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Plant Cell Nucleolus as a Hot Spot for Iron [PDF]
Journal of Biological Chemistry, 2011 Many central metabolic processes require iron as a cofactor and take place in specific subcellular compartments such as the mitochondrion or the chloroplast. Proper iron allocation in the different organelles is thus critical to maintain cell function and integrity.
Roschzttardtz, Hannetz +6 more
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