Results 21 to 30 of about 4,939,783 (282)
C. elegans nucleostemin is required for larval growth and germline stem cell division. [PDF]
PLoS Genetics, 2008 The nucleolus has shown to be integral for many processes related to cell growth and proliferation. Stem cells in particular are likely to depend upon nucleolus-based processes to remain in a proliferative state. A highly conserved nucleolar factor named
Michelle M Kudron, Valerie Reinke
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The structure of the mitotic spindle and nucleolus during mitosis in the amebo-flagellate Naegleria. [PDF]
PLoS ONE, 2012 Mitosis in the amebo-flagellate Naegleria pringsheimi is acentrosomal and closed (the nuclear membrane does not break down). The large central nucleolus, which occupies about 20% of the nuclear volume, persists throughout the cell cycle.
Charles J Walsh
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Nucleolar Organization and Functions in Health and Disease
Cells, 2020 The nucleolus is a prominent, membraneless compartment found within the nucleus of eukaryotic cells. It forms around ribosomal RNA (rRNA) genes, where it coordinates the transcription, processing, and packaging of rRNA to produce ribosomal subunits ...
Ursula Stochaj, Stephanie C. Weber
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Nucleologenesis in the Caenorhabditis elegans embryo. [PDF]
PLoS ONE, 2012 In the Caenorhabditis elegans nematode, the oocyte nucleolus disappears prior to fertilization. We have now investigated the re-formation of the nucleolus in the early embryo of this model organism by immunostaining for fibrillarin and DAO-5, a putative ...
Darina Korčeková +4 more
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Brazilian Journal of Otorhinolaryngology, 2015 INTRODUCTION: Occurrence of apoptosis and expression of proliferative markers are powerful tools to establish a prognosis in the follow-up of cancer.OBJECTIVE: To evaluate the growth fraction in papillomas and laryngeal squamous cell carcinomas with ...
Christiana Vargas Ribeiro +2 more
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Cell Reports, 2016 The nucleolus is the site of rRNA gene transcription, rRNA processing, and ribosome biogenesis. However, the nucleolus also plays additional roles in the cell. We isolated nucleoli using fluorescence-activated cell sorting (FACS) and identified nucleolus-
Frédéric Pontvianne +11 more
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The nucleolus, an ally, and an enemy of cancer cells [PDF]
Histochemistry and Cell Biology, 2018 The rates of ribosome production by a nucleolus and of protein biosynthesis by ribosomes are tightly correlated with the rate of cell growth and proliferation. All these processes must be matched and appropriately regulated to provide optimal cell functioning. Deregulation of certain factors, including oncogenes, controlling these processes, especially
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Nucleolar asymmetry and the importance of septin integrity upon cell cycle arrest. [PDF]
PLoS ONE, 2017 Cell cycle arrest can be imposed by inactivating the anaphase promoting complex (APC). In S. cerevisiae this arrest has been reported to stabilize a metaphase-like intermediate in which the nuclear envelope spans the bud neck, while chromatin repeatedly ...
Urvashi Rai, Fadi Najm, Alan M Tartakoff
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The Multiple Functions of the Nucleolus in Plant Development, Disease and Stress Responses
Frontiers in Plant Science, 2018 The nucleolus is the most conspicuous domain in the eukaryotic cell nucleus, whose main function is ribosomal RNA (rRNA) synthesis and ribosome biogenesis.
Natalia O. Kalinina +5 more
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Nucleolar localization of the ErbB3 receptor as a new target in glioblastoma
BMC Molecular and Cell Biology, 2022 Background The nucleolus is a subnuclear, non-membrane bound domain that is the hub of ribosome biogenesis and a critical regulator of cell homeostasis. Rapid growth and division of cells in tumors are correlated with intensive nucleolar metabolism as a ...
Marzia Tagliaferro +8 more
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