Nature Reviews Molecular Cell Biology, 2007 The nucleolus is a distinct subnuclear compartment that was first observed more than 200 years ago. Nucleoli assemble around the tandemly repeated ribosomal DNA gene clusters and 28S, 18S and 5.8S ribosomal RNAs (rRNAs) are transcribed as a single ...
François-Michel Boisvert +2 more
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C. elegans nucleostemin is required for larval growth and germline stem cell division. [PDF]
PLoS Genetics, 2008 The nucleolus has shown to be integral for many processes related to cell growth and proliferation. Stem cells in particular are likely to depend upon nucleolus-based processes to remain in a proliferative state. A highly conserved nucleolar factor named
Michelle M Kudron, Valerie Reinke
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Rlp7p is associated with 60S preribosomes, restricted to the granular component of the nucleolus, and required for pre-rRNA processing [PDF]
, 2002 Many analyses have examined subnucleolar structures in eukaryotic cells, but the relationship between morphological structures, pre-rRNA processing, and ribosomal particle assembly has remained unclear.
Tollervey, D +13 more
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The structure of the mitotic spindle and nucleolus during mitosis in the amebo-flagellate Naegleria. [PDF]
PLoS ONE, 2012 Mitosis in the amebo-flagellate Naegleria pringsheimi is acentrosomal and closed (the nuclear membrane does not break down). The large central nucleolus, which occupies about 20% of the nuclear volume, persists throughout the cell cycle.
Charles J Walsh
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Nucleolar localization of influenza A NS1: striking differences between mammalian and avian cells [PDF]
, 2010 In mammalian cells, nucleolar localization of influenza A NS1 requires the presence of a C-terminal nucleolar localization signal. This nucleolar localization signal is present only in certain strains of influenza A viruses.
Soubies, S.M. +18 more
core +1 more source
The Trypanosoma cruzi metacyclic-specific protein Met-III associates with the nucleolus and contains independent amino and carboxyl terminal targeting elements. [PDF]
, 2007 Metacyclogenesis in Trypanosoma cruzi involves the differentiation of replicating non-infective epimastigotes into non-replicating metacyclic trypomastigotes.
Gluenz, E +7 more
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Nucleolar Organization and Functions in Health and Disease
Cells, 2020 The nucleolus is a prominent, membraneless compartment found within the nucleus of eukaryotic cells. It forms around ribosomal RNA (rRNA) genes, where it coordinates the transcription, processing, and packaging of rRNA to produce ribosomal subunits ...
Ursula Stochaj, Stephanie C. Weber
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Nucleologenesis in the Caenorhabditis elegans embryo. [PDF]
PLoS ONE, 2012 In the Caenorhabditis elegans nematode, the oocyte nucleolus disappears prior to fertilization. We have now investigated the re-formation of the nucleolus in the early embryo of this model organism by immunostaining for fibrillarin and DAO-5, a putative ...
Darina Korčeková +4 more
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Brazilian Journal of Otorhinolaryngology, 2015 INTRODUCTION: Occurrence of apoptosis and expression of proliferative markers are powerful tools to establish a prognosis in the follow-up of cancer.OBJECTIVE: To evaluate the growth fraction in papillomas and laryngeal squamous cell carcinomas with ...
Christiana Vargas Ribeiro +2 more
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Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins [PDF]
, 2007 Background: The nucleolus is a subnuclear organelle in which rRNAs are transcribed, processed, and assembled with ribosomal proteins into ribosome subunits.
Lamond, Angus I. +13 more
core +1 more source