Results 11 to 20 of about 4,939,783 (282)

Initial genomics of the human nucleolus. [PDF]

open access: yesPLoS Genetics, 2010
We report for the first time the genomics of a nuclear compartment of the eukaryotic cell. 454 sequencing and microarray analysis revealed the pattern of nucleolus-associated chromatin domains (NADs) in the linear human genome and identified different ...
Attila Németh   +9 more
doaj   +3 more sources

Genome Organization in and around the Nucleolus

open access: yesCells, 2019
The nucleolus is the largest substructure in the nucleus, where ribosome biogenesis takes place, and forms around the nucleolar organizer regions (NORs) that comprise ribosomal RNA (rRNA) genes.
Cristiana Bersaglieri, Raffaella Santoro
doaj   +2 more sources

Therapeutic Approaches Targeting Nucleolus in Cancer

open access: yesCells, 2019
The nucleolus is a distinct sub-cellular compartment structure in the nucleus. First observed more than 200 years ago, the nucleolus is detectable by microscopy in eukaryotic cells and visible during the interphase as a sub-nuclear structure immersed in ...
Pietro Carotenuto   +4 more
doaj   +2 more sources

Localisation of the Ki-67 antigen within the nucleolus: Evidence for a fibrillarin-deficient region of the dense fibrillar component [PDF]

open access: yes, 1996
The Ki-67 antigen is detected in proliferating cells in all phases of the cell division cycle. Throughout most of interphase, the Ki-67 antigen is localised within the nucleolus.
Kill, IR
core   +6 more sources

PRC2.1 Coordinates Peri-Nucleolar H3K27me3-Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity. [PDF]

open access: yesAdv Sci (Weinh)
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Zhu L   +12 more
europepmc   +2 more sources

An axiomatization of the nucleolus of the assignment game [PDF]

open access: yes, 2013
[cat] En el domini dels jocs bilaterals d’assignació, es presenta una axiomàtica del nucleolus com l´unica solució que compleix les propietats de consistència respecte del joc derivat definit per Owen (1992) i monotonia de les queixes dels sectors ...
Llerena Garrés, Francesc   +2 more
core   +6 more sources

A geometric chracterization of the nucleolus of the assignment game [PDF]

open access: yes, 2013
Maschler et al. (1979) caracteritzen geomètricament la intersecció del kernel i del core en els jocs cooperatius, demostrant que les distribucions que pertanyen a ambdós conjunts es troben en el punt mig d’un cert rang de negociació entre parelles de ...
Llerena Garrés, Francesc   +2 more
core   +6 more sources

Adeno-associated virus type 2 (AAV2) uncoating is a stepwise process and is linked to structural reorganization of the nucleolus.

open access: yesPLoS Pathogens, 2022
Nucleoli are membrane-less structures located within the nucleus and are known to be involved in many cellular functions, including stress response and cell cycle regulation. Besides, many viruses can employ the nucleolus or nucleolar proteins to promote
Sereina O Sutter   +8 more
doaj   +1 more source

rRNA transcription is integral to phase separation and maintenance of nucleolar structure.

open access: yesPLoS Genetics, 2023
Transcription of ribosomal RNA (rRNA) by RNA Polymerase (Pol) I in the nucleolus is necessary for ribosome biogenesis, which is intimately tied to cell growth and proliferation.
Soma Dash   +13 more
doaj   +1 more source

On the nucleolus of 2 x 2 assignment games (WP) [PDF]

open access: yes, 2013
[spa] En este artículo hallamos fórmulas para el nucleolo de juegos de asignación arbitrarios con dos compradores y dos vendedores. Se analizan cinco casos distintos, dependiendo de las entradas en la matriz de asignación.
Martínez de Albéniz, F. Javier   +2 more
core   +6 more sources

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