Results 91 to 100 of about 63,849 (272)

Axonal regeneration in hippocampal and spinal cord organotypic slice cultures [PDF]

open access: yes, 2010
Under normal conditions, axonal regeneration after lesions is not possible in mature CNS but can occur in embryonic and early postnatal nervous systems. In recent years, a number of possible strategies to enhance axonal regeneration and eventually treat ...
Bonnici, Brenda
core   +1 more source

Physiology–microhabitat matching may help organisms cope with the thermal and hydric challenges under climate change: a tale of two lizards

open access: yesEcography, EarlyView.
Climate change is significantly affecting biodiversity, and organisms that depend on external temperature – such as ectotherms – are particularly vulnerable to these effects. Microhabitats provide refuge for species, thereby reducing exposure to thermal and hydric stress under climate change.
Carolina Reyes‐ Puig   +3 more
wiley   +1 more source

Alteration of 28S rRNA 2′-O-methylation by etoposide correlates with decreased SMN phosphorylation and reduced Drosha levels

open access: yesBiology Open, 2019
The most common types of modification in human rRNA are pseudouridylation and 2′-O ribose methylation. These modifications are performed by small nucleolar ribonucleoproteins (snoRNPs) which contain a guide RNA (snoRNA) that base pairs at specific sites ...
Marilyn F. Burke   +3 more
doaj   +1 more source

An ancestral axial twist explains the contralateral forebrain and the optic chiasm in vertebrates

open access: yes, 2014
Among the best-known facts of the brain are the contralateral visual, auditory, sensational, and motor mappings in the forebrain. How and why did these evolve?
de Lussanet, Marc H. E., Osse, Jan W. M.
core   +1 more source

Signal transmission through the dark-adapted retina of the toad (Bufo marinus). Gain, convergence, and signal/noise. [PDF]

open access: yes, 1990
Responses to light were recorded from rods, horizontal cells, and ganglion cells in dark-adapted toad eyecups. Sensitivity was defined as response amplitude per isomerization per rod for dim flashes covering the excitatory receptive field centers.
Copenhagen, David, Hemilä, S, Reuter, T
core   +2 more sources

Chronic intestinal pseudo-obstruction in a Bernese Mountain Dog [PDF]

open access: yes, 2009
Chronic Intestinal Pseudo-Obstruction (CIPO) is a rare syndrome characterized by chronic intestinal dilation and dysmotility in the absence of mechanical obstruction.
Chiers, Koen   +5 more
core  

Intestinal Electric Stimulation Accelerates Whole Gut Transit and Promotes Fat Excrement in Conscious Rats [PDF]

open access: yes, 2009
*_Introduction:_* Intestinal electric stimulation (IES) is proposed as a potential tool for the treatment of morbid obesity. Our previous study showed that IES with one pair of electrodes accelerated intestinal transit and decreased fat absorption in a ...
Jiande Chen, Ying Sun
core   +2 more sources

siRNA and miRNA processing: new functions for Cajal bodies [PDF]

open access: yesCurrent Opinion in Genetics & Development, 2008
In diverse eukaryotes, micro-RNAs (miRNAs) and small interfering RNAs (siRNAs) regulate important processes that include mRNA inactivation, viral defense, chromatin modification, and transposon silencing. Recently, nucleolus-associated Cajal bodies in plants have been implicated as sites of siRNA and miRNA biogenesis, whereas in animals siRNA and miRNA
Olga, Pontes, Craig S, Pikaard
openaire   +2 more sources

Clinical, manometric, genetic, and histologic associations in pediatric intestinal pseudo‐obstruction: A case series

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric intestinal pseudo‐obstruction (PIPO) is a severe bowel motility disorder characterized by impaired propulsion of gastrointestinal contents without mechanical obstruction. PIPO encompasses congenital and acquired disorders, including neuropathies, myopathies, and mesenchymopathies.
Sharon Wolfson   +8 more
wiley   +1 more source

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