Results 101 to 110 of about 63,849 (272)

Morphologies and potential roles of telocytes in nervous tissue

open access: yesClinical and Translational Discovery, 2023
Structurally similar cells have been found and termed telocytes (TCs) since the first characterisation of interstitial Cajal‐like cells in 1911. TCs are a novel and peculiar interstitial cell type with a small cellular body, markedly long cell processes ...
Xu Zhang, Ping Lu, Xiaorong Shen
doaj   +1 more source

Chewable Soft Gelatin Capsules: Design and Formulation Strategies for a Patient‐Preferred Dosage Alternative

open access: yesMacromolecular Materials and Engineering, EarlyView.
Chewable softgels are a patient‐preferred alternative to conventional oral forms, offering pleasant taste, fast onset, and suitability for children or patients with swallowing difficulties. However, they present relevant challenges in their formulation: the shell must balance chewability, machinability, and stability, while the fill must mask the ...
Almudena Naharros‐Molinero   +3 more
wiley   +1 more source

Hit and run versus long-term activation of PARP-1 by its different domains fine-tunes nuclear processes. [PDF]

open access: yes, 2019
Poly(ADP-ribose) polymerase 1 (PARP-1) is a multidomain multifunctional nuclear enzyme involved in the regulation of the chromatin structure and transcription.
Ampofo, Michelle   +13 more
core   +1 more source

Large-Scale Isolation of Cajal Bodies from HeLa Cells [PDF]

open access: yesMolecular Biology of the Cell, 2002
The Cajal body (CB) is a conserved, dynamic nuclear structure that is implicated in various cellular processes, such as the maturation of splicing small nuclear ribonucleoproteins and the assembly of transcription complexes. Here, we report the first procedure for the large-scale purification of CBs from HeLa cell nuclei, resulting in an ∼750-fold ...
Lam, Yun Wah   +2 more
openaire   +3 more sources

Poly(O‐Propargyl‐N‐Amino Carbamate), a Reactive Polymer to Underpin Biomedical Applications of Poly(acetylene)s

open access: yesMacromolecular Rapid Communications, EarlyView.
We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh   +8 more
wiley   +1 more source

Epstein-Barr virus-induced up-regulation of TCAB1 is involved in the DNA damage response in nasopharyngeal carcinoma

open access: yesScientific Reports, 2017
Telomerase Cajal body protein 1 (TCAB1), which is involved in Cajal body maintenance, telomere elongation and ribonucleoprotein biogenesis, has been linked to cancer predisposition, including nasopharyngeal carcinoma (NPC), due to its oncogenic ...
Kun Wang   +10 more
doaj   +1 more source

Cajal bodies and snRNPs - friends with benefits [PDF]

open access: yesRNA Biology, 2016
Spliceosomal snRNPs are complex particles that proceed through a fascinating maturation pathway. Several steps of this pathway are closely linked to nuclear non-membrane structures called Cajal bodies. In this review, I summarize the last 20 y of research in this field. I primarily focus on snRNP biogenesis, specifically on the steps that involve Cajal
openaire   +2 more sources

Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor   +3 more
wiley   +1 more source

Oncogene SCARNA12 as a potential diagnostic biomarker for colorectal cancer

open access: yesMolecular Biomedicine, 2023
Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive system, and represents a severe threat to the life and health of individuals.
Hong Zhang   +10 more
doaj   +1 more source

A statistical method for measuring the Galactic potential and testing gravity with cold tidal streams [PDF]

open access: yes, 2012
We introduce the Minimum Entropy Method, a simple statistical technique for constraining the Milky Way gravitational potential and simultaneously testing different gravity theories directly from 6D phase-space surveys and without adopting dynamical ...
Binney   +16 more
core   +3 more sources

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