Results 121 to 130 of about 63,849 (272)

Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]

, 2016
Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E., Capani, Francisco, Castilla Lozano, Maria del Rocio, Holubiec, Mariana Ines, Logica Tornatore, Tamara Maite Ayelén, Riviere, Stephanie   +5 more
core   +1 more source

Of coilin and Cajal bodies

The Journal of Cell Biology, 2001
![][1] Addition of coilin (green) recruits SMN (red) to Cajal bodies. A nuclear protein is labeled in magenta. Cajal bodies (CBs), until recently known as coiled bodies, are revealed by silver staining as prominent spots in nuclei.
openaire   +2 more sources

Monovalent mannose‐glycoconjugates of sulforaphane reprogram human dendritic cells via NFATc1 to induce immune tolerance under inflammatory conditions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez, Camila Leiva‐Castro, Ana M. Múnera‐Rodríguez, Macarena Martínez‐Bailén, Ana T. Carmona, Soledad López‐Enríquez, Francisca Palomares   +6 more
wiley   +1 more source

Income taxes and redistribution in the early twentieth century

The Economic History Review, EarlyView.
Abstract This paper examines the distributive effects of personal income taxation in Sweden, the United Kingdom, and the United States during the first half of the twentieth century. We estimate the evolution of marginal and average effective tax rates across the income distribution and calculate the corresponding indices of progressivity and ...
Sara Torregrosa‐Hetland, Oriol Sabaté
wiley   +1 more source

Cajal body finds its function

The Journal of Cell Biology, 2002
The Cajal body (CB, formerly coiled body) is a prominent nuclear structure, yet its function remains obscure. Now, Xavier Darzacq, Tamas Kiss (CNRS, Universite Paul Sabatier, Toulouse, France), and colleagues speculate that the CB is where small nuclear RNAs go for modification. Figure Novel guide RNAs localize to CBs.
openaire   +2 more sources

Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease

Epilepsia, EarlyView.
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa, Laura Bellingacci, Jacopo Canonichesi, Valentina Imperatore, Anna Aurora Taddei, Luis Zafra‐Puerta, Nerea Iglesias‐Cabeza, Paolo Prontera, Andrea Mancini, Massimiliano Di Filippo, Alessandro Tozzi, Katiuscia Martinello, Marta Barzasi, Fabrizio Gardoni, Marina P. Sánchez, José M. Serratosa, Lucilla Parnetti, Miriam Sciaccaluga   +17 more
wiley   +1 more source

Wild bee diversity and land use: A case study in a mountain agroecosystem of the Serranía de Ronda, southern Spain

Insect Conservation and Diversity, EarlyView.
Orchards supported the highest wild bee diversity and functional diversity, highlighting their role in maintaining bee communities in Mediterranean agroecosystems. Landscape heterogeneity positively influenced functional evenness and dispersion of wild bee communities, underscoring the importance of diverse landscapes for bee conservation. The presence
Violeta Hevia, Francisco M. Azcárate, Jorge Chicote, Federica Ravera   +3 more
wiley   +1 more source

Cajal Bodies and Oral Squamous Cell Carcinoma.

The journal of contemporary dental practice, 2019
Oral squamous cell carcinoma (OSCC) is a complex disease with heterogeneity in its clinical and pathological presentation as well as phenotypic and biologic behavior. Despite tremendous advancements in the field of genomics and technology, this particular entity still continues to contribute significantly to the mortality rates worldwide.1 Research ...
Gargi, Sarode, Nikunj, Maniyar, Sachin C, Sarode, Dharmarajan, Gopalkrishnan, Shankargouda, Patil   +4 more
openaire   +3 more sources

Building the foundations for an international patient‐centred outcomes set for psoriasis: A scoping study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This scoping study refined the first patient‐centred outcome set for psoriasis, involving patient representatives and dermatologists from 22 countries. The proposal includes 18 patient‐relevant outcomes, 2 patient experiences, corresponding outcome measurement instruments and 50 case‐mix variables.
Emma Vyvey, Rani Soenen, Hazel H. Oon, Sicily Mburu, Maren Awici‐Rasmussen, Azura Mohd Affandi, Wayne Gulliver, Siew Eng Choon, Tiago Torres, Allison FitzGerald, Alvaro Gonzalez‐Cantero, Anna López‐Ferrer, Chih‐Hung Lee, Fernando Valenzuela, Julia‐Tatjana Maul, Luis Puig, Masanori Okuse, Mohamed EL‐Komy, Peter Foley, Ron Vender, Wolf‐Henning Boehncke, Josef Pohunek, Ya Hsin Wang, Angela Londoño‐García, Gail Todd, Margarita Velasquez‐Lopera, Mark Lebwohl, Edmund Lau, Marcus Schmitt‐Egenolf, Niels Hilhorst, Spencer Connell, Elfie Deprez, Nanja van Geel, Christopher Griffiths, Peter Van de Kerkhof, Jo Lambert   +35 more
wiley   +1 more source

Coilin mediates m6A RNA methylation through phosphorylation of METTL3

Biology Open, 2023
Douglas M. McLaurin, Sara K. Tucker, Michael D. Hebert   +2 more
doaj   +1 more source