Results 21 to 30 of about 63,849 (272)
Vitamin C enhances co-localization of novel TET1 nuclear bodies with both Cajal and PML bodies in colorectal cancer cells [PDF]
EpigeneticsDeregulation of ten-eleven Translocation protein 1 (TET1) is commonly reported to induce imbalances in gene expression and subsequently to colorectal cancer development (CRC).
Nour El Osmani +8 more
doaj +2 more sources
Towards an understanding of regulating Cajal body activity by protein modification. [PDF]
RNA Biol, 2017 Hebert MD, Poole AR.
europepmc +3 more sources
RNA Biology, 2016 Cajal is commonly regarded as the father of modern neuroscience in recognition of his fundamental work on the structure of the nervous system. But Cajal also made seminal contributions to the knowledge of nuclear structure in the early 1900s, including the discovery of the "accessory body" later renamed "Cajal body" (CB).
Miguel Lafarga +3 more
openalex +3 more sources
Monoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity. [PDF]
Hum Mol Genet, 2016 Han KJ +5 more
europepmc +3 more sources
The fission yeast ortholog of Coilin, Mug174, forms Cajal body-like nuclear condensates and is essential for cellular quiescence. [PDF]
Nucleic Acids ResDeng X +6 more
europepmc +2 more sources
Coilin as a regulator of NF-kB mediated inflammation in preeclampsia
Biology Open, 2022 The nuclear factor-Kappa B (NF-κB) pathway is a crucial mediator of inflammatory signaling. Aberrant activation of NF-κB is associated with several disorders including preeclampsia (PE).
Madelyn K. Logan +3 more
doaj +1 more source
The Cajal body and histone locus body. [PDF]
Cold Spring Harb Perspect Biol, 2010 The Cajal body (CB) is a nuclear organelle present in all eukaryotes that have been carefully studied. It is identified by the signature protein coilin and by CB-specific RNAs (scaRNAs). CBs contain high concentrations of splicing small nuclear ribonucleoproteins (snRNPs) and other RNA processing factors, suggesting that they are sites for assembly and/
Nizami Z, Deryusheva S, Gall JG.
europepmc +4 more sources
Specific genomic cues regulate Cajal body assembly. [PDF]
RNA Biol, 2017 The assembly of specialized sub-nuclear microenvironments known as nuclear bodies (NBs) is important for promoting efficient nuclear function. In particular, the Cajal body (CB), a prominent NB that facilitates spliceosomal snRNP biogenesis, assembles in response to genomic cues.
Sawyer IA, Hager GL, Dundr M.
europepmc +4 more sources
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source