A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II [PDF]
, 2014 Cajal bodies are nuclear structures that are involved in biogenesis of snRNPs and snoRNPs, maintenance of telomeres and processing of histone mRNA. Recently, the SUMO isopeptidase USPL1 was identified as a component of Cajal bodies that is essential for ...
Andersen +95 more
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A Viral Suppressor of RNA Silencing May Be Targeting a Plant Defence Pathway Involving Fibrillarin
Plants, 2022 To establish productive infections, viruses must be able both to subdue the host metabolism for their own benefit and to counteract host defences. This frequently results in the establishment of viral–host protein–protein interactions that may have ...
Miryam Pérez-Cañamás +2 more
doaj +1 more source
A perspective on cortical layering and layer-spanning neuronal elements [PDF]
, 2018 This review article addresses the function of the layers of the cerebral cortex. We develop the perspective that cortical layering needs to be understood in terms of its functional anatomy, i.e., the terminations of synaptic inputs on distinct cellular ...
Larkum, Matthew E. +3 more
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Changes in interstitial cells and gastric excitability in a mouse model of sleeve gastrectomy.
PLoS ONE, 2022 Obesity is a critical risk factor of several life-threatening diseases and the prevalence in adults has dramatically increased over the past ten years.
Suk Bae Moon +7 more
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New clues to the function of the Cajal body [PDF]
EMBO reports, 2002 Small RNA molecules play major roles in a number of cellular functions. Depending on their predominant cellular location, small RNAs have been classified as nuclear (sn), nucleolar (sno) or cytoplasmic (sc). The nucleoplasmic species include the spliceosomal snRNAs (U1, U2, U4, U5 and U6) and the U7 snRNA required for histone pre‐mRNA 3′‐end formation.
Maria Carmo‐Fonseca
openalex +5 more sources
Small Cajal Body–specific RNAs ofDrosophilaFunction in the Absence of Cajal Bodies [PDF]
Molecular Biology of the Cell, 2009 During their biogenesis small nuclear RNAs (snRNAs) undergo multiple covalent modifications that require guide RNAs to direct methylase and pseudouridylase enzymes to the appropriate nucleotides. Because of their localization in the nuclear Cajal body (CB), these guide RNAs are known as small CB-specific RNAs (scaRNAs).
Svetlana, Deryusheva, Joseph G, Gall
openaire +2 more sources
Perceived Vertical and Lateropulsion: Clinical Syndromes, Localization, and Prognosis [PDF]
, 2000 We present a clinical classification of central vestibular syndromes according to the three major planes of action of the vestibulo-ocular reflex: yaw, roll, and pitch.
Brandt +3 more
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Regulation of neuronal differentiation by proteins associated with nuclear bodies. [PDF]
PLoS ONE, 2013 Nuclear bodies are large sub-nuclear structures composed of RNA and protein molecules. The Survival of Motor Neuron (SMN) protein localizes to Cajal bodies (CBs) and nuclear gems.
Benjamin Förthmann +10 more
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Wiring optimization explanation in neuroscience: What is Special about it? [PDF]
, 2019 This paper examines the explanatory distinctness of wiring optimization models in neuroscience. Wiring optimization models aim to represent the organizational features of neural and brain systems as optimal (or near-optimal) solutions to wiring ...
Barberis, Sergio Daniel
core +6 more sources
Silencing TCAB1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosis
Türk Biyokimya Dergisi, 2023 Telomerase Cajal body protein 1 (TCAB1) is closely related to the occurrence, development and prognosis of tumors, and may affect the sensitivity of tumor radiotherapy.
Zhang Guangmou +3 more
doaj +1 more source