Results 51 to 60 of about 63,849 (272)
Biology Open, 2014 Spliceosomal small nuclear ribonucleoproteins (snRNPs) are enriched in the Cajal body (CB). Guide RNAs, known as small Cajal body-specific RNAs (scaRNAs), direct modification of the small nuclear RNA (snRNA) component of the snRNP.
Isioma I. Enwerem +5 more
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WRAP53 Unwrapped; Roles in Nuclear Architecture and Cancer [PDF]
, 2011 WRAP53 is a gene of multiple functions; it encodes for a natural antisense transcript that regulates the actions of the tumour suppressor p53, and it gives rise to a protein with oncogenic properties that is important for Cajal body formation and ...
Mahmoudi, Salah
core +1 more source
Identification of additional regulatory RNPs that impact rRNA and U6 snRNA methylation
Biology Open, 2018 Ribosomes can be heterogeneous, and the major contributor to ribosome heterogeneity is variation in rRNA modification. There are two major types of rRNA modification, pseudouridylation and ribose methylation.
Marilyn F. Burke +2 more
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In vivo kinetics of Cajal body components [PDF]
The Journal of Cell Biology, 2004 Cajal bodies (CBs) are subnuclear domains implicated in small nuclear ribonucleoprotein (snRNP) biogenesis. In most cell types, CBs coincide with nuclear gems, which contain the survival of motor neurons (SMN) complex, an essential snRNP assembly factor. Here, we analyze the exchange kinetics of multiple components of CBs and gems in living cells using
Dundr, M. +9 more
openaire +3 more sources
Phosphorylation regulates coilin activity and RNA association
Biology Open, 2013 Summary The Cajal body (CB) is a domain of concentrated components found within the nucleus of cells in an array of species that is functionally important for the biogenesis of telomerase and small nuclear ribonucleoproteins.
Hanna J. Broome +3 more
doaj +1 more source
Transcriptome profiling reveals significant changes in the gastric muscularis externa with obesity that partially overlap those that occur with idiopathic gastroparesis [PDF]
, 2019 BACKGROUND: Gastric emptying is impaired in patients with gastroparesis whereas it is either unchanged or accelerated in obese individuals. The goal of the current study was to identify changes in gene expression in the stomach muscularis that may be ...
Chen, Meng +7 more
core +1 more source
Identification of Functional Domain(s) of Fibrillarin Interacted with p2 of Rice stripe virus
Canadian Journal of Infectious Diseases and Medical Microbiology, 2018 p2 of Rice stripe virus may promote virus systemic infection by interacting with the full length of fibrillarin from Nicotiana benthamiana (NbFib2) in the nucleolus and cajal body (CB). NbFib2 contains three functional domains.
Luping Zheng +4 more
doaj +1 more source
Biology Open, 2018 Small Cajal body-specific RNAs (scaRNAs) are part of small Cajal body-specific ribonucleoproteins (scaRNPs) that modify small nuclear RNA (snRNA) in Cajal bodies (CBs).
Madelyn K. Logan +2 more
doaj +1 more source
Smoking affects gene expression in blood of patients with ischemic stroke. [PDF]
, 2019 ObjectiveThough cigarette smoking (CS) is a well-known risk factor for ischemic stroke (IS), there is no data on how CS affects the blood transcriptome in IS patients.MethodsWe recruited IS-current smokers (IS-SM), IS-never smokers (IS-NSM), control ...
Ander, Bradley P +6 more
core +2 more sources
Frontiers in Cellular Neuroscience, 2019 Santiago Ramón y Cajal was still young when he came across the reazione nera, discovered by the Italian Camillo Golgi. Cajal became absolutely entranced by the fine structure of the nervous system this technique revealed, which led him to embark on one ...
Fernando de Castro
doaj +1 more source