Results 61 to 70 of about 2,971 (203)

Further Oxidation of Hydroxycalcidiol by Calcidiol 24‐Hydroxylase [PDF]

open access: yesEuropean Journal of Biochemistry, 1994
The coding region of the cDNA for rat kidney calcidiol 24‐hydroxylase (P450cc24), which is involved in calcium homeostasis in animals, was inserted into an expression vector pKK223‐3. The recombinant plasmid was formed in a specific manner without deletion or substitution of any parts of the coding region of the cDNA.
M, Akiyoshi-Shibata   +5 more
openaire   +2 more sources

A Multidomain Lifestyle Intervention Is Associated With Improved Functional Trajectories and Favorable Changes in Epigenetic Aging Markers in Frail Older Adults: A Randomized Controlled Trial

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
In frail older adults, a 6‐month lifestyle intervention slowed epigenetic aging and improved functional outcomes, suggesting lifestyle strategies may delay biological aging and disability progression. ABSTRACT Frailty emerges as the intermediate stage preceding disability, but there is a gap in molecular signatures for early detection of subclinical ...
Gloria Olaso‐Gonzalez   +13 more
wiley   +1 more source

Benefits of vitamin D supplementation to attenuate TBI secondary injury?

open access: yesTranslational Neuroscience, 2021
Vitamin D supplementation has been shown to improve outcomes for patients suffering from a variety of illnesses such as stroke and cancer. Vitamin D deficiencies have been associated with longer hospital stays, greater severity of symptoms, and death in ...
Saadatmand Kiana   +6 more
doaj   +1 more source

Integrative Toxicology Profiling of Thuja sutchuenensis Essential Oil: From LD50 Safety Assessment to Hepatic Apoptosis and Gut Microbiota Modulation

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
This study provides the first experimental evidence of Thuja sutchuenensis essential oil (TEO) toxicity, with an oral LD50 of ~3800 mg/kg in mice. Sub‐LD50 doses cause focal hepatic necrosis via apoptosis/oxidative stress–related pathways without systemic inflammation or renal injury.
Nana Long   +8 more
wiley   +1 more source

Analysis of risk factors for decreased calcidiol levels in late postmenopausal women: Results of a cross‑sectional study [PDF]

open access: yes, 2023
The aim of the study was to assess the contribution of the most significant vitamin D deficiency risk factors to calcidiol supply in late postmenopausal Ekaterinburg residents.Цель исследования — оценка вклада наиболее значимых факторов риска дефицита ...
Izmozherova, N. V.   +7 more
core  

Nutritional Deficiencies Following Bariatric Surgery: A Rapid Systematic Review of Case Reports of Vitamin and Micronutrient Deficiencies Presenting More Than Two Years Post‐Surgery

open access: yesClinical Obesity, Volume 15, Issue 6, December 2025.
ABSTRACT Bariatric surgery is the most clinically‐ and cost‐effective intervention for severe obesity. However, without adequate follow‐up, it can lead to nutritional deficiencies. Patients require life‐long nutritional supplements and follow‐up to prevent nutritional deficiencies from developing.
Sophie Haughton   +2 more
wiley   +1 more source

Biological markers of suicidal behavior and justification of use level calzidiola in the blood

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2019
The article is devoted to the problem of search of biomarkers of suicidal behavior and includes literature review, as well as the results of own research of features of suicidal behavior of young age patients with depression (18—27 years) depending on ...
N. N. Petrova   +4 more
doaj   +1 more source

sj-docx-1-cpj-10.1177_00099228231204444 – Supplemental material for Association of Blood Calcidiol Levels and Metabolic Syndrome in Children and Adolescents With Vitamin D Deficiency

open access: yes, 2023
Supplemental material, sj-docx-1-cpj-10.1177_00099228231204444 for Association of Blood Calcidiol Levels and Metabolic Syndrome in Children and Adolescents With Vitamin D Deficiency by Fernando A. Isart, Fernando Jose Isart-Infante and R.
Fernando A. Isart (17414135)   +2 more
core   +1 more source

Analysis of Potential Vitamin D Molecule Biomarkers: Association of Calcitriol and Its Hydroxylation Efficiency Ratio with Cardiovascular Disease Risk in Rheumatoid Arthritis Patients

open access: yesBiomedicines
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease in which hypovitaminosis D by calcidiol quantification has been associated with disease severity.
Melissa Rivera-Escoto   +9 more
doaj   +1 more source

Serum 25‐hydroxyvitamin D concentration and infectious respiratory disease complex in shelter dogs

open access: yesJournal of Veterinary Internal Medicine, 2021
Background Hypovitaminosis D is a risk factor for the development of respiratory infections in humans and repletion can be protective. Objectives Determine if serum 25‐hydroxyvitamin (OH)D concentrations are lower in shelter dogs and if 25(OH)D ...
Jared A. Jaffey   +8 more
doaj   +1 more source

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