Results 71 to 80 of about 2,971 (203)

Vitamin D Deficiency as a Debatable Modulator of Outcomes in Transfusion‐Dependent Thalassemia; An Overview of the Latest Findings: A Narrative Review

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Vitamin D deficiency (VDD) is highly prevalent in transfusion‐dependent thalassemia (TDT), yet its clinical implications beyond bone health remain controversial. This review explores the risk factors and clinical outcomes of VDD in TDT, with particular focus on its potential roles in cardiac iron deposition, osteoporosis ...
Ali Bazi, Mahdieh Poodineh Moghadam, Jafar Baranipour, Hajar Noori Sanchooli, Hamed Soleimani Samarkhazan, Omolbanin Sargazi Aval, Mojtaba Aghaei   +6 more
wiley   +1 more source

The Efficacy and Safety of High-Dose Cholecalciferol Therapy in Hemodialysis Patients

Biomedicines
Vitamin D deficiency and insufficiency are highly prevalent in CKD, affecting over 80% of hemodialysis (HD) patients and requiring therapeutic intervention. Nephrological societies suggest the administration of cholecalciferol according to the guidelines
Agnieszka Tarasewicz, Michał Komorniczak, Agnieszka Zakrzewska, Bogdan Biedunkiewicz, Sylwia Małgorzewicz, Magdalena Jankowska, Katarzyna Jasiulewicz, Natalia Płonka, Małgorzata Dąbrowska, Alicja Dębska-Ślizień, Leszek Tylicki   +10 more
doaj   +1 more source

Data for the article "Increased calcidiol level in redhaired people: Could redheadedness be an adaptation to temperate climate?"

, 2019
About 1–2% of European population are redhaired, meaning they synthesize pheomelanin instead of eumelanin, the main melanin pigment. Several mutations could be responsible for this phenotype.
Jaroslav Flegr (771164)
core   +1 more source

Impact of aging on cardiovascular dynamics and heart rate variability during passive head‐up tilt

Physiological Reports, Volume 13, Issue 14, July 2025.
Abstract During aging, arterial stiffness and blood pressure (BP) increase, while heart rate variability (HRV) decreases. We examined age‐related hemodynamics in 522 individuals without cardiovascular disease during passive head‐up tilt (HUT) using pulse wave analysis, whole‐body impedance cardiography, and HRV analysis.
Manoj Kumar Choudhary, Kati Holmström, Heidi Bouquin, Tuomas P. Saarinen, Jenni K. Koskela, Essi Pietilä, Lauri Suojanen, Jukka T. Mustonen, Pasi I. Nevalainen, Ilkka H. Pörsti   +9 more
wiley   +1 more source

Factors affecting vitamin D status in Moscow adolescents

Медицинский совет, 2019
Justification of the study. The normalization of vitamin D levels in both children and adults is the goal of numerous studies around the world, and the setting of a number of objectives related to this vector of preventive medicine, dictates the need for
I. N. Zakharova, E. A. Solov’yeva, T. M. Tvorogova, S. I. Lazareva, T. Yu. Vil’ken, N. G. Sugyan   +5 more
doaj   +1 more source

Metabolism of calcidiol and calcium in pregnant and lactating goats

Regulatory Mechanisms in Biosystems
The aim of our study was to investigate the dynamics of the metabolism of one of the active metabolites of vitamin D – 25OHD 3 and its effect on the metabolism of total and ionized calcium in pregnant and lactating goats. The subject of the study was Z aanen and L aman goats: pregnant (75–90 and 120–140 days of pregnancy) and lactating animals (0–2 and
V. Sakhniuk, M. Hotsuliak, A. Melnyk, V. Marchuk, M. Samoray, M. Utechenko   +5 more
openaire   +1 more source

Conservative treatment of bone tissue metabolic disorders among patients with vitamin D-dependent rickets type II with genetic abnormality of type I collagen formation

Bolʹ, Sustavy, Pozvonočnik, 2017
Background. The purpose of the article is to determine the effect of conservative therapy on genetically caused disorders of bone tissue metabolism in patients with vitamin D-dependent rickets type II and genetic abnormality of type I collagen formation (
S.M. Martsyniak
doaj   +1 more source

A single-oral bolus of 100,000 IU of cholecalciferol at hospital admission did not improve outcomes in the COVID-19 disease: the COVID-VIT-D—a randomised multicentre international clinical trial

BMC Medicine, 2022
Background Vitamin D status has been implicated in COVID-19 disease. The objective of the COVID-VIT-D trial was to investigate if an oral bolus of cholecalciferol (100,000 IU) administered at hospital admission influences the outcomes of moderate-severe ...
Jorge B. Cannata-Andía, Augusto Díaz-Sottolano, Pehuén Fernández, Carmen Palomo-Antequera, Pablo Herrero-Puente, Ricardo Mouzo, Natalia Carrillo-López, Sara Panizo, Guillermo H. Ibañez, Carlos A. Cusumano, Carolina Ballarino, Vicente Sánchez-Polo, Jacqueline Pefaur-Penna, Irene Maderuelo-Riesco, Jesús Calviño-Varela, Mónica D. Gómez, Carlos Gómez-Alonso, John Cunningham, Manuel Naves-Díaz, Walter Douthat, José L. Fernández-Martín, the COVID-VIT-D trial collaborators   +21 more
doaj   +1 more source

Niveles de calcidiol en pacientes pediátricos con obesidad

, 2020
Objetive: Verify if obesity causes calcidiol deficiency in children and if this deficit causes secondary hyperparathyroidism. Materials and methods: We compare different analytical and anthropometric values among children with obesity followed in the ...
Ontoria Betancort, Cristina, Carballo Martín, Pedro, Martín Fernández De Basoa, María Cecilia, Ruiz Pons, Mónica, García Nieto, Víctor Manuel, Roa Prieto, Manuel, Díaz Martín, Cristina   +6 more
core  

Safety and efficacy of a feed additive consisting of 25‐hydroxycholecalciferol produced with Saccharomyces cerevisiae CBS 146008 for salmonids, other fish species and all other animal species (except poultry, pigs and all ruminants) (DSM Nutritional Products Ltd.)

EFSA Journal, Volume 23, Issue 6, June 2025.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 25‐hydroxycholecalciferol as a nutritional feed additive for salmonids, other fish species and all other animal species (except poultry, pigs and all ruminants).
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Vasileios Bampidis, Noël Dierick, Montserrat Anguita, Rosella Brozzi, Matteo L. Innocenti, Fabiola Pizzo, Jordi Tarrés‐Call, Angelica Amaduzzi   +24 more
wiley   +1 more source