Results 1 to 10 of about 531,192 (386)
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype [PDF]
Nature Genetics, 2019 Aortic calcification is an important independent predictor of future cardiovascular events. We performed a genome-wide association meta-analysis to determine SNPs associated with the extent of abdominal aortic calcification (n = 9,417) or descending ...
Rajeev Malhotra +49 more
core +5 more sources
Clinicopathological Features of Anticancer Drug-induced Kidney Injury [PDF]
Zhongguo quanke yixue, 2022 Background The prevalence of anticancer drug-induced kidney injury is increasing, but related renal pathology studies are still rare. Objective To analyze the clinicopathological characteristics of patients with anticancer drug-related kidney injury ...
GENG Tonghui, LI Han, JIN Jingjing, CHENG Meijuan, ZHANG Shenglei, BAI Yaling, XU Jinsheng
doaj +1 more source
Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox
Nature Communications, 2022 Adipocyte differentiation of bone marrow mesenchymal stem/stromal cells (BMSCs) instead of osteoblast formation contributes to age- and menopause-related marrow adiposity and osteoporosis.
Zhenxing Wang +24 more
semanticscholar +1 more source
Microbiome, 2022 Background Vascular calcification is a major cause of the high morbidity and mortality of cardiovascular diseases and is closely associated with the intestinal microbiota. Short-chain fatty acids (SCFAs) are derived from the intestinal microbiota and can
Jianlong Yan +13 more
semanticscholar +1 more source
Autophagic LC3+ calcified extracellular vesicles initiate cartilage calcification in osteoarthritis
Science Advances, 2022 Pathological cartilage calcification plays an important role in osteoarthritis progression but in which the origin of calcified extracellular vesicles (EVs) and their effects remain unknown.
Jianfei Yan +15 more
semanticscholar +1 more source
BMC Cardiovascular Disorders, 2023 Objectives This study aimed to analyze the possible causes of changes in cardiac function and investigate the feasibility of clinical assessment of gastrointestinal cancer in patients with or without acute kidney injury (AKI) assessed using a non ...
Huihui Chen +13 more
doaj +1 more source
Correlation between serum level of PARP1 and vascular calcification in hemodialysis patients
Linchuang shenzangbing zazhi, 2023 Objective To explore the correlation between serum level of poly(ADP-ribose) polymerase 1 (PARP1) and vascular calcification in hemodialysis (HD) patients.
Hui Zhang +4 more
doaj +1 more source
Vascular Calcification—New Insights into Its Mechanism
International Journal of Molecular Sciences, 2020 Vascular calcification (VC), which is categorized by intimal and medial calcification, depending on the site(s) involved within the vessel, is closely related to cardiovascular disease.
S. Lee, In-kyu Lee, Jae-Han Jeon
semanticscholar +1 more source
Vascular Calcification: Key Roles of Phosphate and Pyrophosphate
International Journal of Molecular Sciences, 2021 Cardiovascular complications due to accelerated arterial stiffening and atherosclerosis are the leading cause of morbimortality in Western society. Both pathologies are frequently associated with vascular calcification.
R. Villa-Bellosta
semanticscholar +1 more source
Predictors for Rapid Progression of Coronary Calcification: An Optical Coherence Tomography Study
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background The role of coronary calcification in cardiovascular events and plaque stabilization is still being debated, and factors involved in the progression of coronary calcification are not fully understood.
Akihiro Nakajima +12 more
doaj +1 more source