Results 261 to 270 of about 22,950 (306)

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source

Trends in kidney stone prevalence among U.S. adults A concerning contemporary gender analysis from the NHANES database. [PDF]

Can Urol Assoc J
Chen KW, Meskawi M, Miller LE, Bhattacharyya S, Tailly T, Chew BH, Bhojani N.   +6 more
europepmc   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

Advanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He, Zhidong Wei, Jianda Xu, Fei Jin, Tong Li, Lili Qian, Juan Ma, Weiying Zheng, Negar Javanmardi, Ting Wang, Kangjian Sun, Zhang‐Qi Feng   +11 more
wiley   +1 more source

Widespread scope for coral adaptation under combined ocean warming and acidification. [PDF]

Proc Biol Sci
Jury CP, Toonen RJ.
europepmc   +1 more source

Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α

Advanced Science, EarlyView.
NEU1, a key regulator of glycolysis, is markedly upregulated following DOX treatment. This upregulation is attributed to HIF1α’s transcriptional repression, requiring intricate interactions with NRF2. Increased NEU1 facilitates SIRT1 lysosomal degradation, contributing to aberrant glycolytic phenotype and cardiac damage.
Ting Gao, Yufeng Tang, Tao Zeng, Jie Wang, Xiaohui Zhang, Qingbo Liu, Xun Guan, Xinyu Tang, Guangping Lu, Jiahao Li, Mingrui Liu, Dongmei Zhang, Sixuan Lv, Junlian Gu   +13 more
wiley   +1 more source

Dysregulation of Mitochondrial Homeostasis in Cardiovascular Diseases. [PDF]

Pharmaceuticals (Basel)
Patil R, Wang H, Kazaleh M, Ailawadi G, Salmon M.   +4 more
europepmc   +1 more source

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

Advanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang, Mingyue Fan, Su Chin Heo, Sheila M. Adams, Thomas Li, Yuchen Liu, Qing Li, Claudia Loebel, Jason A. Burdick, X. Lucas Lu, David E. Birk, Farid Alisafaei, Robert L. Mauck, Lin Han   +13 more
wiley   +1 more source

An imaging and diagnostic conundrum-the adrenal haemangioma. [PDF]

J Surg Case Rep
Tan T, Diab J, Chia P, Singh A, Campbell P, Guevara R.   +5 more
europepmc   +1 more source

Physiology and functional significance of the coronary microcirculation: An overview of its implications in health and disease. [PDF]

Am Heart J Plus
Alam S, Pepine CJ.
europepmc   +1 more source

Hyperprolactinemia complicated with peliosis hepatis: One case report and review of literature. [PDF]

Medicine (Baltimore)
Li X, Lv Y, Xia Y, Lai Y, Chen S, Xie Y, Tang Z, Cheng Q.   +7 more
europepmc   +1 more source