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Circulation Research, 2020 Supplemental Digital Content is available in the text. Rationale: Vascular calcification, the formation of calcium phosphate crystals in the vessel wall, is mediated by vascular smooth muscle cells (VSMCs).
M. Furmanik +15 more
semanticscholar +1 more source
Cardiovascular Research, 2018 Vascular calcification is associated with a significant increase in all-cause mortality and atherosclerotic plaque rupture. Calcification has been determined to be an active process driven in part by vascular smooth muscle cell (VSMC ...
A. Durham +4 more
semanticscholar +1 more source
CALCIFICATION OF THE PINEAL [PDF]
The Journal of Nervous and Mental Disease, 1918 n ...
Boas,, Scholz,
openaire +3 more sources
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.
Genes & Development, 1998 Osteoprotegerin (OPG) is a secreted protein that inhibits osteoclast formation. In this study the physiological role of OPG is investigated by generating OPG-deficient mice.
N. Bucay +11 more
semanticscholar +1 more source
Calcification of subcutaneously implanted collagens in relation to cytotoxicity, cellular interactions and crosslinking [PDF]
, 1995 In general, calcification of biomaterials occurs through an interaction of host and implanted material factors, but up to now the real origin of pathologic calcification is unknown.
Dijkstra, P.J. +4 more
core +3 more sources
From variome to phenome : pathogenesis, diagnosis and management of ectopic mineralization disorders [PDF]
, 2015 Ectopic mineralization - inappropriate biomineralization in soft tissues - is a frequent finding in physiological aging processes and several common disorders, which can be associated with significant morbidity and mortality.
De Vilder, eva, Vanakker, Olivier
core +2 more sources
Research Models for Studying Vascular Calcification [PDF]
, 2020 Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality. Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting factors in an actively regulated process.
Babic, Milen +4 more
core +1 more source
Arteriosclerosis, Thrombosis and Vascular Biology, 2019 Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood vessel degenerates, leading to dilation and eventually vessel wall rupture.
Ploingarm Petsophonsakul +9 more
semanticscholar +1 more source
Aldosterone is a possible new stimulating factor for promoting vascular calcification
Frontiers in Bioscience-Landmark, 2021 Background: Aldosterone is an important hormone in the renin-angiotensin-aldosterone system (RAAS), and playing a pivotal role in the development of hypertension, heart failure, and other cardiovascular diseases.
Xusheng Zhang +6 more
doaj +1 more source