Results 151 to 160 of about 2,749 (172)

ChemInform Abstract: Synthesis of Calcimycin (A 23187) Biomimetic Models. Preparation of Spiroacetal Intermediate.

ChemInform, 1988
AbstractThe reaction between the pyrroles (I) and the aldehyde (II) represents the starting step in the synthesis of the spiroacetals (III).
M. PRUDHOMME, G. DAUPHIN, G. JEMINET
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Interaction of the calcium ionophore A.23187 (Calcimycin) with Bacillus cereus and Escherichia coli

Letters in Applied Microbiology, 1993
Ionophores isolated from bacterial strains, and especially A.23187, are efficient antibiotics against Gram-positive bacteria and devoid of activity on Gram-negative species. This difference in activity was attributed to the outer membrane of Gram-negative bacteria which is presumably impermeable to these very hydrophobic compounds. In this context, the
J. Guyot, G. Jeminet, Michelle Prudhomme, Martine Sancelme, R. Meiniel   +4 more
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[4‐³H]‐labelling of the calcium ionophore A 23187 (calcimycin)

Journal of Labelled Compounds and Radiopharmaceuticals, 1989
Abstract[4‐3H‐labelled]‐A 23187 (or calcimycin) has been obtained as a magnesium salt from the corresponding 4‐bromo derivative using tritiated hydrogen gas in the presence of 10% Pd/C catalyst. The specific radioactivity proved to be 50.6 Ci/mmole (1872.2 GBq/m mole).
M. Prudhomme, G. Jeminet, D. Schott, J. L. Morgat, P. Beaulieu   +4 more
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Characterization of the N-methyltransferase CalM involved in calcimycin biosynthesis by Streptomyces chartreusis NRRL 3882

Biochimie, 2013
Calcimycin is a rare divalent cation specific ionophore antibiotic that has many biochemical and pharmaceutical applications. We have recently cloned and sequenced the Streptomyces chartreusis calcimycin biosynthesis gene cluster as well as identified the genes required for the synthesis of the polyketide backbone of calcimycin. Additional modifying or
Qiulin, Wu, Lixia, Gou, Shuangjun, Lin, Jingdan, Liang, Jun, Yin, Xiufen, Zhou, Linquan, Bai, Derong, An, Zixin, Deng, Zhijun, Wang   +9 more
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Closely related ionophores cezomycin and calcimycin (A 23187): cooperative formation of the transporting species

Inorganic Chemistry, 1994
Cezomycin, a biosynthetic analogue of calcimycin (A 23187), was studied to evaluate the effect of changes in structural features on the coordination and transport of calcium and magnesium. Its protonation and calcium and magnesium complexation properties were examined at equilibrium in pure methanol using potentiometric and spectrophotometric methods ...
A. M. Albrecht-Gary, S. Blanc, L. David, G. Jeminet   +3 more
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X-14885A: an ionophore closely related to calcimycin (A-23187). NMR, thermodynamic, and kinetic studies of cation selectivity

Journal of the American Chemical Society, 1989
X-14885A is an open-chain carboxylic ionophore, recently isolated from a Streptomyces strain. NMR data have shown that the free acid form adopts a pseudocyclic conformation in chloroform, while in the neutral A 2Mg complex a rotation of the benzoxazole arm is achieved to accommodate the cation in a sandwich system.
Albrecht-Gary, Anne-Marie, Blanc, Sylvie, Boyd, D.W., Dauphin, G., Jeminet, Georges, Juillard, Jean, Prudhomme, Michelle, Tissier, C.   +7 more
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Synthetic Studies on Antibiotic A23187 (Calcimycin)

HETEROCYCLES, 1984
Akira Fujita, Yoshiaki Nakahara, Tomoya Ogawa   +2 more
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[Inhibitory effect of dauricine on platelet activating factor released from calcimycin-induced mouse peritoneal macrophages].

Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991
The effects of dauricine (Dau) on the release of platelet activating factor (PAF) from mouse peritoneal macrophages stimulated by calcimycin (A-23187) was studied. The method of sodium [3H]acetate incorporating into macrophages to synthesize PAF was set up for the first time.
G Q, Zeng, Y C, Rui
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ESAT-6 impedes IL-18 mediated phagosome lysosome fusion via microRNA-30a upon Calcimycin treatment in mycobacteria infected macrophages

International Immunopharmacology, 2021
Assirbad Behura, Mousumi Das, Lincoln Naik   +2 more
exaly  

SYNTHETIC STUDIES TOWARDS CALCIMYCIN

1981
P.A. Grieco, E. Williams, Ken-ichi Kanai
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