A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies [PDF]
Objectives: The paediatric idiopathic inflammatory myopathies (IIMs) are a group of rare chronic inflammatory disorders of childhood, affecting muscle, skin and other organs.
Bohan +50 more
core +1 more source
Mitral valve calcinosis as an important finding during heart examination [PDF]
BACKGROUND: Mitral valve calcinosis is a chronic degenerative process in the fibrous structures of the mitral valve. Advanced stages increase the risk of endocarditis and cardiac rhythm disturbances and contribute to cardiovascular mortality.
Daria A. Filatova +4 more
doaj +1 more source
From variome to phenome : pathogenesis, diagnosis and management of ectopic mineralization disorders [PDF]
Ectopic mineralization - inappropriate biomineralization in soft tissues - is a frequent finding in physiological aging processes and several common disorders, which can be associated with significant morbidity and mortality.
De Vilder, eva, Vanakker, Olivier
core +2 more sources
Calcinosis Cutis of the Nasal Dorsum
Summary:. Calcinosis cutis is a common dermatological problem in patients with systemic sclerosis, dermatomyositis, and systemic lupus erythematous; however, it is rare to occur outside of these diseases.
Henry R. Marsh, BS +3 more
doaj +1 more source
Innate Immunity in Calcinosis Cutis
Calcinosis cutis is the deposition of calcium salts in the skin and subcutaneous tissue, manifesting as variably shaped papules, nodules, and plaques that can substantially impair quality of life.
Simon W. Jiang +2 more
doaj +1 more source
Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. [PDF]
OBJECTIVES: To study muscle biopsy tissue from patients with juvenile dermatomyositis (JDM) in order to test the reliability of a score tool designed to quantify the severity of histological abnormalities when applied to biceps humeri in addition to ...
Amato, Anthony A +19 more
core +3 more sources
Calcinosis cutis is a condition of accumulation of calcium salts within the dermis. The clinco-radiologic features of a 60 year old lady with idiopathic calcinosis cutis is reported. Emphasis on appropriate laboratory workup is crucial once the diagnosis
Nawaz Usman
doaj +1 more source
Metastatic Calcinosis of Gastric Mucosa
Calcinosis cutis refers to the deposition of calcium salts in the cutaneous and subcutaneous tissue and is frequently associated with inflammation. Gastric calcinosis can be classified into metastatic, dystrophic, and idiopathic; metastatic calcinosis is
Vatsalya Kosuru MD +6 more
doaj +1 more source
Nuclear matrix protein 2 antibody-positive adult dermatomyositis: a case report and review of the literature [PDF]
Dermatomyositis is a clinically heterogenous inflammatory myopathy with unique cutaneous features. Myositis-specific antibodies can aid in diagnosis and anticipation of patient prognosis.
Cartron, Alexander M +3 more
core
Evaluation of dystrophic calcinosis in juvenile dermatomyositis and systemic sclerosis
Background: Dystrophic calcinosis is associated with juvenile dermatomyositis and systemic sclerosis. Clini- cal diagnosis is performed through the detection of sub- cutaneous, hard nodules.
Saéz Ocariz Marimar +2 more
doaj +1 more source

