Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. [PDF]
OBJECTIVES: To study muscle biopsy tissue from patients with juvenile dermatomyositis (JDM) in order to test the reliability of a score tool designed to quantify the severity of histological abnormalities when applied to biceps humeri in addition to ...
Amato, Anthony A+19 more
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Teaching Point: The imaging clues to differentiate idiopathic tumoral calcinosis from other calcified soft tissue lesions include: pseudotumoral appearance with mass effect, bone erosion with intra-osseous protrusion of calcification, lobulated morphology, and peri-articular location on the extensor side.
Jesper Dierickx, Filip Vanhoenacker
openaire +7 more sources
Evaluation of dystrophic calcinosis in juvenile dermatomyositis and systemic sclerosis
Background: Dystrophic calcinosis is associated with juvenile dermatomyositis and systemic sclerosis. Clini- cal diagnosis is performed through the detection of sub- cutaneous, hard nodules.
Saéz Ocariz Marimar+2 more
doaj +1 more source
Nicotinamide treatment in a murine model of familial tumoral calcinosis reduces serum Fgf23 and raises heart calcium [PDF]
Mutations in the GALNT3 gene result in familial tumoral calcinosis, characterized by persistent hyperphosphatemia and ectopic calcific masses in soft tissues.
Gray, Amie K.+3 more
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Systemic sclerosis – metamorphosis of a life [PDF]
Systemic sclerosis is a complex autoimmune disorder marked by heterogeneous clinical manifestations and variable disease course. We present the case of a patient with diffuse cutaneous systemic sclerosis with anti-PM/Scl antibodies and associated ...
Andra-Patricia Stanciu+2 more
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Metastatic Calcinosis of Gastric Mucosa
Calcinosis cutis refers to the deposition of calcium salts in the cutaneous and subcutaneous tissue and is frequently associated with inflammation. Gastric calcinosis can be classified into metastatic, dystrophic, and idiopathic; metastatic calcinosis is
Vatsalya Kosuru MD+6 more
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Nuclear matrix protein 2 antibody-positive adult dermatomyositis: a case report and review of the literature [PDF]
Dermatomyositis is a clinically heterogenous inflammatory myopathy with unique cutaneous features. Myositis-specific antibodies can aid in diagnosis and anticipation of patient prognosis.
Cartron, Alexander M+3 more
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Surgical Excision of Tumoral Calcinosis of the Distal End of the Clavicle in a Patient With Uremia [PDF]
Tumoral calcinosis is an uncommon disease characterized by tumor-like lesions composed of calcium salt. This condition is not a true neoplasm but an imbalance of calcium and phosphorus metabolism resulting from hereditary causes or secondary defects ...
Chang, Hui-Mei+2 more
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Calcinosis cutis is a condition of accumulation of calcium salts within the dermis. The clinco-radiologic features of a 60 year old lady with idiopathic calcinosis cutis is reported. Emphasis on appropriate laboratory workup is crucial once the diagnosis
Nawaz Usman
doaj +1 more source
Disseminated cutaneous gout: a rare manifestation of a common disease [PDF]
Disseminated cutaneous gout is a rare atypical cutaneous manifestation of gout in which widespread dermal and subcutaneous tophi develop at extra-articular body sites.
Adler, Brandon L+4 more
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