Results 61 to 70 of about 101,964 (348)

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

How to integrate monoclonal antibodies targeting the calcitonin gene-related peptide or its receptor in daily clinical practice

The Journal of Headache and Pain, 2019
BackgroundMigraine is a major public health issue associated with significant morbidity, considerable negative impact on quality of life, and significant socioeconomic burden.
C. Tiseo, R. Ornello, F. Pistoia, S. Sacco   +3 more
semanticscholar   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

The Role of Calcitonin in Predicting the Extent of Surgery in Medullary Thyroid Carcinoma: A Nationwide Population-Based Study in Norway

European Thyroid Journal, 2019
Background: Preoperative predictors for the need of prophylactic lymph node dissection in the lateral neck have been studied in patients with medullary thyroid carcinoma (MTC). Objectives: To evaluate the ability of serum calcitonin to predict the extent
Else Marie Opsahl, L. Akslen, E. Schlichting, T. Aas, K. Brauckhoff, A. I. Hagen, A. F. Rosenlund, E. Sigstad, K. Grøholt, L. Jørgensen, T. Bjøro   +10 more
semanticscholar   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

The Comparison of Effects of Alendronate and Calcitonin Treatment in Men With Osteoporosis

Türk Osteoporoz Dergisi, 2004
In recent years, there has been a dramatic increase in research investigating the epidemiology, diagnosis, prevention, and treatment of osteoporosis and fragility fractures in men.
Gülcan Gürer, Faruk Şendur, Ayhan Erkek   +2 more
doaj  

Determinants of circulating calcitonin value: analysis of thyroid features, demographic data, anthropometric characteristics, comorbidities, medications, and smoking habits in a population with histological full exclusion of medullary thyroid carcinoma

Frontiers in Oncology
ObjectiveCalcitonin (Ctn) measurement is crucial for the early diagnosis of medullary thyroid carcinoma (MTC). However, Ctn levels can be skewed/elevated due to other reasons, and the Ctn upper reference value remains controversial.
Pierpaolo Trimboli, Pierpaolo Trimboli, Giuseppe Peloni, Dorotea Confalonieri, Elena Gamarra, Tommaso Piticchio, Francesco Frasca, Petra Makovac, Arnoldo Piccardo, Lorenzo Ruinelli, Lorenzo Ruinelli, Lorenzo Ruinelli   +11 more
doaj   +1 more source

Metastatic Medullary Thyroid Carcinoma with Normal Serum Calcitonin Levels

AACE Clinical Case Reports, 2018
: Objective: Medullary thyroid carcinomas (MTCs) originate from parafollicular C cells and produce the hormone calcitonin, which is primarily responsible for the biochemical dysfunction in calcium metabolism seen in MTC. MTCs constitute only about 5 to 7%
Tania Tofail, MRCP, Mohammed Fariduddin, DEM, MD, Tahniyah Haq, MRCP, MS, MD, Shahjada Selim, MD, Sharmin Jahan, FCPS, MD, Morshed Ahmed Khan, MD, Marufa Mustari, FCPS, Hurjahan Banu, FCPS, Rafiqul Alam, FCPS, AminulIslam Joarder, FCPS, Mohammed Kamal, MD, Muhammad Abul Hasanat, MPhil, MD   +11 more
doaj   +1 more source

Calcitonin and calcitonin receptors: bone and beyond

International Journal of Experimental Pathology, 2000
Calcitonin (CT), a 32 amino acid peptide hormone produced primarily by the thyroid, and its receptor (CTR) are well known for their ability to regulate osteoclast mediated bone resorption and enhance Ca2+ excretion by the kidney. However, recent studies now suggest that CT and CTRs may play an important role in a variety of processes as wide ranging as
openaire   +3 more sources

Safety, Tolerability, and Pharmacokinetics of Galcanezumab, an Anti‐CGRP Antibody, in Healthy Chinese Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Galcanezumab is used in several regions, including the United States, Europe, and China, as a preventive treatment for migraine. This study aimed to evaluate the safety, tolerability, and pharmacokinetics (PK) of galcanezumab in healthy Chinese participants.
Jingjing Wang, Nanyang Li, Jinjie He, Jing Zhang, Lili Wang, William Kielbasa, Chenxi Qian, Yanjie Zhang, Liang Wang   +8 more
wiley   +1 more source