Results 81 to 90 of about 155,757 (387)

Calcitonin-gene related peptide and disease activity in cluster headache

Cephalalgia, 2019
Objective To investigate the role of calcitonin gene-related peptide, pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) and vasoactive intestinal polypeptide in cluster headache, we measured these vasoactive peptides interictally and during
A. Snoer, A. L. Vollesen, Rasmus P Beske, Song Guo, Jan Hoffmann, Jan Fahrenkrug, N. R. Jørgensen, T. Martinussen, R. Jensen, M. Ashina   +9 more
semanticscholar   +1 more source

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Unusual increase in carcinoembryonic antigen despite response to selpercatinib in two patients with medullary thyroid cancer

European Thyroid Journal, 2023
Introduction: Serum calcitonin (CT) and carcinoembryonic antigen (CEA) are valuable tumour markers in patients with medullary thyroid carcinoma (MTC). Both markers most often evolve in parallel after treatment.
Stéphane Bardet, Renaud Ciappuccini, Livia Lamartina, Sophie Leboulleux   +3 more
doaj   +1 more source

A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

Advanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren, Zhaojun Wu, Anhang Wu, Hui Zhang, Jiachen Lu, Jiahao Zhang, Jie Weng, Jinhua Zhang, Song Chen, Huan Tan, Tailin Guo   +10 more
wiley   +1 more source

Early postoperative calcitonin-to-preoperative calcitonin ratio as a predictive marker for structural recurrence in sporadic medullary thyroid cancer: A retrospective study

Frontiers in Endocrinology, 2022
BackgroundCalcitonin (Ctn) is widely used as a marker in the diagnosis, prognosis, and postoperative follow-up of patients with medullary thyroid carcinoma (MTC).
Zan Jiao, Zan Jiao, Tong Wu, Tong Wu, Mingjie Jiang, Mingjie Jiang, Shuxian Jiang, Ke Jiang, Ke Jiang, Jin Peng, Jin Peng, Guangfeng Luo, Guangfeng Luo, Yongchao Yu, Yongchao Yu, Weichao Chen, Weichao Chen, Ankui Yang, Ankui Yang   +18 more
doaj   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng, Shuangyu Liu, Yu Zhang, Kang Peng, Muge Qile, Chao Wu, Mengyun Dou, Liu Liu, Na Yang, Rui Liu, Guiyang Zhang, Liangping Ni, Gaolin Liang, Fang Yang, Ye Zhang, Shufang He   +15 more
wiley   +1 more source

Unilateral Surgery for Medullary Thyroid Carcinoma: Seeking for Clinical Practice Guidelines

Frontiers in Endocrinology, 2022
Optimized preoperative diagnostic tools with calcitonin tests, ultrasound features, functional imaging modalities, and genetic testing to detect hereditary forms have led to an increased rate of earlier diagnosis and surgery for medullary thyroid cancer (
Daqi Zhang, Carla Colombo, Carla Colombo, Hui Sun, Hoon Yub Kim, Antonella Pino, Antonella Pino, Simone De Leo, Giacomo Gazzano, Luca Persani, Luca Persani, Gianlorenzo Dionigi, Gianlorenzo Dionigi, Laura Fugazzola, Laura Fugazzola   +14 more
doaj   +1 more source

Calcitonin gene-related peptide and pain: a systematic review

The Journal of Headache and Pain, 2017
BackgroundCalcitonin gene-related peptide (CGRP) is widely distributed in nociceptive pathways in human peripheral and central nervous system and its receptors are also expressed in pain pathways. CGRP is involved in migraine pathophysiology but its role
Wendy Sophie Schou, S. Ashina, F. Amin, P. Goadsby, M. Ashina   +4 more
semanticscholar   +1 more source

Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database

Arthritis &Rheumatology, Accepted Article.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Distinct subpopulations of enteric neuronal progenitors defined by time of development, sympathoadrenal lineage markers and Mash-1-dependence [PDF]

, 1996
Enteric and sympathetic neurons have previously been proposed to be lineally related. We present independent lines of evidence that suggest that enteric neurons arise from at least two lineages, only one of which expresses markers in common with ...
Anderson, D. J., Blaugrund, E., Gershon, M. D., Lo, L., Pham, T. D., Sommer, L., Tennyson, V. M.   +6 more
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