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Raynaud's Phenomenon Associated With Calcitonin Gene‐Related Peptide Monoclonal Antibody Antagonists

Headache, 2019
Two cases are reported of migraineurs who reported Raynaud's phenomenon (RP) exacerbated while taking monoclonal antibodies to the calcitonin gene‐related peptide (CGRP) ligand (fremanezumab and galcanezumab) and 1 case of new onset RP while taking the ...
R. Evans
semanticscholar   +1 more source

Safety and tolerability of calcitonin-gene-related peptide binding monoclonal antibodies for the prevention of episodic migraine – a meta-analysis of randomized controlled trials

Cephalalgia, 2019
Aim To systematically evaluate the safety and tolerability of calcitonin-gene-related peptide binding monoclonal antibodies from the results of randomized controlled trials.
Da Xu   +6 more
semanticscholar   +1 more source

Amylin, Calcitonin Gene-Related Peptide, Calcitonin, and Adrenomedullin: A Peptide Superfamily

Critical Reviews™ in Neurobiology, 1997
The calcitonin gene peptide superfamily consists of calcitonin (CT), calcitonin gene-related peptide (CGRP), and amylin. CT and CGRP derive from the CT/CGRP gene, which is encoded on chromosome 11. Alternative splicing of the primary RNA transcript leads to the translation of CGRP and CT peptides in a tissue-specific manner.
openaire   +2 more sources

Calcitonin gene-related peptide as inflammatory mediator

Pulmonary Pharmacology & Therapeutics, 2003
Sensory neuropeptides have been proposed to play a key role in the pathogenesis of a number of respiratory diseases such as asthma, chronic obstructive pulmonary disease or chronic cough. Next to prominent neuropeptides such as tachykinins or vasoactive intestinal polypeptide (VIP), calcitonin gene-related peptide (CGRP) has long been suggested to ...
J. Springer   +3 more
openaire   +4 more sources

Calcitonin gene-related peptide and the kidney

Current Opinion in Nephrology and Hypertension, 1994
Calcitonin gene-related peptide (CGRP) is a recently discovered neurotransmitter that is extensively localized in fibers innervating vascular and endocrine systems. CGRP possesses potent vasorelaxant effects, and a role for this peptide in the regional regulation of blood flow has been suggested. Although pharmacologic evidence indicates that the renal
D, Villarreal, G, Reams, R, Freeman
openaire   +2 more sources

Calcitonin gene-related peptide is a potent vasodilator

Nature, 1985
S. Brain   +4 more
semanticscholar   +1 more source

Calcitonin Gene-Related Peptide

2016
C.M. Kieffer, P.W. Abel
openaire   +2 more sources

[Calcitonin gene-related peptide (CGRP)].

Presse medicale (Paris, France : 1983), 1994
Calcitonin gene-related peptide (CGRP), a 37 amino acid peptide resulting from the specific maturation processes of calcitonin gene products, was discovered in 1982. Its messenger RNA was isolated from a calcitonin cancer in rats similar to the human thyroid medullary carcinoma.
A, Raynaud, R, Cohen, E, Modigliani
openaire   +1 more source

The Effects of Calcitonin Gene-Related Peptide on Bone Homeostasis and Regeneration

Current Osteoporosis Reports, 2020
Jiankun Xu   +5 more
semanticscholar   +1 more source

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