Results 61 to 70 of about 13,600,961 (272)

Calcitonin gene-related peptide regulates periodontal tissue regeneration

Scientific Reports
Calcitonin gene-related peptide (CGRP), a neuropeptide composed of 37 amino acids secreted from the sensory nerve endings, reportedly possesses various physiological effects, such as vasodilation and neurotransmission.
Koji Miki, Noboru Takeshita, Motozo Yamashita, Masahiro Kitamura, Shinya Murakami   +4 more
doaj   +1 more source

Ultra-high field MR angiography in human migraine models: a 3.0 T/7.0 T comparison study

The Journal of Headache and Pain, 2019
Background Sildenafil and calcitonin gene-related peptide both dilate the intradural segments of the middle meningeal artery measured with 3.0 tesla (T) MR angiography.
Casper Emil Christensen, Samaira Younis, Ulrich Lindberg, Vincent Oltman Boer, Patrick de Koning, Esben Thade Petersen, Olaf Bjarne Paulson, Henrik Bo Wiberg Larsson, Faisal Mohammad Amin, Messoud Ashina   +9 more
doaj   +1 more source

Inducible Laryngeal Obstruction in Hypermobile Patients

The Laryngoscope, EarlyView.
Patients with hypermobile Ehlers‐Danlos syndrome (hEDS) or hypermobility spectrum disorders (HSD) who screened positive for inducible laryngeal obstruction (ILO) reported significantly greater voice, cough, swallowing, gastrointestinal, and mast cell‐related symptoms than those without ILO. Chronic cough, dysphagia, and elevated mast cell symptom score
Stacey M. Menton, DeLisa Fairweather, Frances C. Wilson, Derek J. Zangerle, Emma F. Murphy, Ashley A. Darakjian, Chandler C. Thompson, Shilpa N. Gajarawala, Dacre R. T. Knight, Katelyn A. Bruno, Amy L. Rutt   +10 more
wiley   +1 more source

Three‐Dimensional Immunofluorescence Analysis of Psoriatic Plaques Before and After Pulsed Dye Laser Treatment: Reduced T‐Cell Content Without Changes in Nerve Fiber or Blood Vessel Density

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Pulsed dye laser (PDL) treatment for psoriasis has demonstrated its potential for treatment‐free remission periods exceeding 1 year. The mechanism leading to remission is not fully understood, but PDL is known to heat the vasculature in the skin. We hypothesized that heat diffuses from the vasculature to the surrounding environment,
Meagan Doppegieter, Nick van der Beek, Judith de Vos, H.A. Martino Neumann, Maurice C. G. Aalders, Erik N. T. P. Bakker, Ton G. van Leeuwen   +6 more
wiley   +1 more source

Safety and Efficacy of 10 kHz Spinal Cord Stimulation for the Treatment of Refractory Chronic Migraine: A Prospective Long‐Term Open‐Label Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Refractory chronic migraine (rCM) is a highly disabling condition for which novel safe and effective treatments are needed. Safety and long‐term efficacy of paresthesia‐free high cervical 10 kHz spinal cord stimulation (SCS) were here prospectively evaluated for the treatment of rCM.
Adnan Al‐Kaisy, Stefano Palmisani, Roy Carganillo, Samuel Wesley, David Pang, Anand Rotte, Angela Santos, Giorgio Lambru   +7 more
wiley   +1 more source

Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells

Respiratory Research, 2009
Background Alveolar epithelial cells are known as progenitor cells for the restoration from the damage in the lung. Calcitonin gene-related peptide (CGRP) has been reported to play an important role in the proliferation of various types of epithelial and
Yatera Kazuhiro, Asonuma Etsuko, Kido Takashi, Machida Kazuhiko, Nakamura Takehiro, Kim Heungnam, Morimoto Yasuo, Kawanami Yukiko, Yoshii Chiharu, Kido Masamitsu   +9 more
doaj   +1 more source

Hypersensitivity to calcitonin gene-related peptide in chronic migraine

, 2020
Objective: To investigate if calcitonin gene-related peptide infusion induces migraine-like attacks in chronic migraine patients. Methods: Fifty-eight patients with chronic migraine, either with or without headache on the experimental day, were assessed ...
Ashina, Håkan, Zhuang, Zixuan Alice, Lopez Lopez, Cristina, Snellman, Josefin, Ashina, Messoud, Iljazi, Afrim, Schytz, Henrik Winther, Josefin Snellman, Afrim Iljazi, Håkan Ashina, Cristina Lopez Lopez, Zixuan Alice Zhuang, Messoud Ashina, Henrik Winther Schytz   +13 more
core   +1 more source

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

Innovative 3D‐bioprinted microfibers in calcium phosphate cement platform with Nell‐1 to activate nerve‐bone axis for synergistic bone, vasculature, and nanofibrous nerve regeneration

Smart Molecules, EarlyView.
A 3D‐bioprinted platform with stem cells activates “nerve‐bone” signaling by enabling the spatiotemporal delivery of Nell‐1. This activation enhances neurovascular and bone regeneration through the CYFIP1 cascade. In rat calvarial defects, the platform doubled bone regeneration and nerve repair and tripled vascular density, resulting in superior ...
Minjia Zhu, Xinyi Li, Jingyi Li, Kan Yu, Zixiang Dai, Le Xiao, Qinrou Zhang, Zihan Jia, Qingchen Qiao, Zeqing Zhao, Ke Zhang, Yuxing Bai   +11 more
wiley   +1 more source

Real-world effectiveness of erenumab in Japanese patients with migraine

Heliyon
Background: Real-world evidence of erenumab effectiveness in migraine patients in Asia with various comorbidities and multiple previous medication failures is still limited.
Keisuke Suzuki, Shiho Suzuki, Tomohiko Shiina, Yasuo Haruyama, Saro Kobayashi, Mukuto Shioda, Koichi Hirata   +6 more
doaj   +1 more source