Results 111 to 120 of about 49,400 (296)

1,25-OH2 vitamin D3 and AKT-inhibition increase glucocorticoid induced apoptosis in a model of T-cell acute lymphoblastic leukemia (ALL)

Leukemia Research Reports, 2018
In acute lymphoblastic leukemia (ALL), steroid resistance and hypovitaminosis D are both associated with a poor prognosis. We show that methylprednisolone, calcitriol and the AKT-inhibitor MK-2206 have a synergistic effect on the apoptosis of steroid ...
Maximilian Pistor, Lisa Schrewe, Steffen Haupeltshofer, Andrei Miclea, Simon Faissner, Andrew Chan, Robert Hoepner   +6 more
doaj  

The Vertebral Column of Flatfish: A Review

Reviews in Aquaculture, Volume 17, Issue 4, September 2025.
ABSTRACT Flatfish (Pleuronectiformes) encompass fascinating fish species known for their high gastronomical value, rearing performances, and market prices, which attract both economic and scientific interest. Despite these attributes, flatfish exhibit unique morphological, developmental, and biological features, as well as distinctive swimming ...
A. M. de Azevedo, A. P. Losada, S. Vázquez, P. E. Witten, M. I. Quiroga, P. J. Gavaia   +5 more
wiley   +1 more source

Effects of calcitriol on random skin flap survival in rats

Scientific Reports, 2016
Calcitriol, a metabolite of vitamin D, is often used in osteoporosis clinics. However, the material has other bioactivities; for example, it accelerates angiogenesis, has anti-inflammatory properties and inhibits oxidative stress.
Kailiang Zhou, Yi-hui Zhang, D. Lin, X. Tao, Hua‐zi Xu   +4 more
semanticscholar   +1 more source

Chronic Kidney Disease in Cats and the Risk of Total Hypercalcemia [PDF]

, 2017
BACKGROUND: Chronic kidney disease (CKD) is a common comorbidity in cats with hypercalcemia, but whether CKD is a risk factor for hypercalcemia is unclear.
Abdi, Andress, Barber, Barber, Barber, Berend, Berry, Bertazzolo, Bienzle, Blaine, Block, Burnell, Bushinsky, Chakrabarti, Cole, Costanzo, DiBartola, Elliott, Elliott, Eren, Finch, Flanders, Fogh-Andersen, Gal, Gauci, Geddes, Geddes, He, Jackson, Kelly, Kogika, Kovesdy, Kurz, Lemann, Levi, Levi, Lulich, Malatesha, Marino, Marone, McLeland, Meghji, Meuten, Midkiff, Must, Payne, Peacock, Picolos, Pieper, Piraino, Polzin, Rafferty, Savary, Schenck, Schenck, Schenck, Schenck, Schenck, Schenck, Schenck, Shanahan, Shipov, Sutton, Tentori, Williams, Yamada, Yang   +66 more
core   +1 more source

Utilization and expenditure on medicines for the management of osteoporosis in Ireland: A repeated cross‐sectional study

British Journal of Clinical Pharmacology, Volume 91, Issue 8, Page 2283-2293, August 2025.
Aim Osteoporosis is a prevalent skeletal disease characterized by low bone mass and increased fracture risk. Management of osteoporosis typically involves antiresorptive and anabolic therapies, which are reimbursed in Ireland through various drug schemes.
Amelia Smith, Lisa Kelly, Claire Gorry, Bernard Duggan, Michael Barry   +4 more
wiley   +1 more source

Effects of vitamin D3 derivative--calcitriol on pharmacological reactivity of aortic rings in a rodent PCOS model. [PDF]

, 2014
BACKGROUND: The aim of this study was to examine the effects of the hyperandrogenic state in dihydrotestosterone (DHT)-induced polycystic ovary syndrome (PCOS), the vascular responses to different vasoactive agents, and the modulatory role of vitamin ...
Benko, Rita, Benyó, Zoltán, Buday, A., Hamar, P., Horváth, Eszter Mária, Masszi, G., Novak, A., Nádasy, György László, Revesz, C., Ruisanchez, Éva, Sara, L., Tarszabo, R., Tőkés, Anna-Mária, Várbíró, Szabolcs   +13 more
core  

Effect of Calcitriol on Differentiation of Periodontal Ligament Stem Cells to Osteoblasts [PDF]

, 2016
Background: Periodontium may be able to respond to injuries by regeneration via the function of stem cells. Objectives: This study sought to assess the differentiation of human periodontal ligament stem cells (PDLSCs) into osteoblasts in standard ...
Amiri, Iraj., Bidgoli, Mohsen., Hedayatipanah, Morad., Momeni, Mohammad Ali., Moradi Haghgoo, Janet., Soheilifar, Sara.   +5 more
core   +1 more source

Neuroprotective Potential of Curcumin in Neurodegenerative Diseases: Clinical Insights Into Cellular and Molecular Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 8, August 2025.
Curcumin regulates several signaling pathways linked to neuroprotection, such as those that reduce oxidative stress, prevent Aβ formation, and decrease neuroinflammation. ABSTRACT Progressive neuronal loss and dysfunction characterize neurodegenerative diseases (NDs) such as Alzheimer's, Parkinson's, and Huntington's diseases, spinal cord injury, and ...
Md. Rezaul Islam, Abdur Rauf, Sumiya Akter, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Md. Tazul Islam, Hassan A. Hemeg, Waleed Al Abdulmonem, Abdullah S. M. Aljohani, Marcello Iriti   +11 more
wiley   +1 more source

Effects of calcitriol (1, 25-dihydroxy-vitamin D3) on the inflammatory response induced by H9N2 influenza virus infection in human lung A549 epithelial cells and in mice

Virology Journal, 2017
BackgroundH9N2 influenza viruses circulate globally and are considered to have pandemic potential. The hyper-inflammatory response elicited by these viruses is thought to contribute to disease severity.
Boxiang Gui, Qin Chen, Chuanxia Hu, Caihui Zhu, G. He   +4 more
semanticscholar   +1 more source

Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma [PDF]

, 2012
Basal cell carcinoma (BCC) of the skin is the most common type of cancer, and accounts for up to 40% of all cancers in the United States with a growing incidence rate in the last decades in all developed countries.
CUCCHI, DANILO, DE SMAELE, Enrico, GULINO, Alberto, OCCHIONE, MARIA ANNA   +3 more
core   +3 more sources