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Current Vascular Pharmacology, 2014
The synthesis of 1α,25-dihydroxyvitamin D3 (Calcitriol) takes place mostly in the kidneys through the action of 1α-hydroxylase (CYP27B1) which converts 25(OH)D into 1,25(OH)2D3. Renal production of calcitriol is stimulated by PTH, low calcium and low phosphate and it is reduced by high phosphate and FGF23.
Mariano, Rodriguez +2 more
openaire +2 more sources
The synthesis of 1α,25-dihydroxyvitamin D3 (Calcitriol) takes place mostly in the kidneys through the action of 1α-hydroxylase (CYP27B1) which converts 25(OH)D into 1,25(OH)2D3. Renal production of calcitriol is stimulated by PTH, low calcium and low phosphate and it is reduced by high phosphate and FGF23.
Mariano, Rodriguez +2 more
openaire +2 more sources
Calcitriol in dialysis patients
Clinical Pharmacology & Therapeutics, 1978We conducted a 7‐month randomized, single, double, single‐blind comparison of calcitriol (1,25(OH)2D3) with vitamin D3 in 22 hemodialysis patients to study the effects on the biochemical abnormalities associated with osteodystrophy. Calcitriol was given for 3 mo.
D R, Maxwell +5 more
openaire +2 more sources
Combinations of Calcitriol with Anticancer Treatments for Breast Cancer: An Update
International Journal of Molecular Sciences, 2021Mariana Segovia-Mendoza +2 more
exaly