Results 1 to 10 of about 12,305 (169)

Association of rs2476601 and rs1544410 with Onset of T1D in Youngsters of Lahore, Pakistan

Journal of Bioresource Management, 2016
The PTPN22 gene plays vital role in T1D onset by encoding Lymphoid-specific phosphatase (LYP) that lead to T-cell receptor-associated CsK kinase inactivation and preventing T-cell spontaneous activation by dephosphorylation.
Andleeb Batool, Maryam Mukhtar, Iram Qayyum, Romessa Shakeel   +3 more
doaj   +1 more source

Association of vitamin D receptor gene fok1 polymorphism with bone health in Pakistani population

Journal of Biochemical and Clinical Genetics, 2020
Background: Osteoporosis is the bone disease characterized by demineralization of the bone. One of the most important genetic factors responsible for the osteoporosis is the vitamin D receptor (VDR) gene polymorphism.
Najam Farooq, Anwar Ullah, Abida Arshad, Navida Riaz, Jabar Zaman Khan, Sobia Tabassum, Muhammad Arshad Malik   +6 more
doaj   +1 more source

Association of Single-Nucleotide Polymorphisms in the VDR Gene with Tuberculosis and Infection of Beijing Genotype Mycobacterium tuberculosis

Infection and Drug Resistance, 2023
Jinjie Yu,1,2,* Mengwen Liu,3,* Xiaokaiti Mijiti,4,* Haican Liu,2,* Quan Wang,4 Chunjie Yin,3 Aiketaguli Anwaierjiang,5 Miao Xu,4 Machao Li,2 Lele Deng,2,6 Hui Xiao,3 Xiuqin Zhao,2 Kanglin Wan,2 Guilian Li,2 Xiuqin Yuan1 1School of Public Health ...
Yu J, Liu M, Mijiti X, Liu H, Wang Q, Yin C, Anwaierjiang A, Xu M, Li M, Deng L, Xiao H, Zhao X, Wan K, Li G, Yuan X   +14 more
doaj  

A simple and sensitive method to detect vitamin D receptor expression in various disease models using stool samples

Genes and Diseases, 2021
Vitamin D receptor (VDR) executes the main biological functions of its ligand vitamin D. VDR/vitamin D plays critical roles in regulating host immunity, maintaining barrier functions, and shaping gut microbiome.
Yong-guo Zhang, Yinglin Xia, Jun Sun
doaj   +1 more source

Correlation of vitamin D receptor and TIMP-1 expression in placenta accreta spectrum: an immunohistochemical study [PDF]

Romanian Medical Journal
Introduction. Placenta accreta is one of the high-risk pregnancy conditions and remains one of the major pregnancyrelated problems in Indonesia. Given the abnormal trophoblast invasion into the myometrium that characterizes this condition, VDR and TIMP-1
Yoga Paripurna, Hanom Husni Syam, Sonny Sasotya, Jusuf S. Effendi, Setyorini Irianti, Siti Salima   +5 more
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Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic MiceSummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: Observational epidemiologic studies have associated vitamin D deficiency with cholestasis. We reported previously that activation of the vitamin D/vitamin D receptor (VDR) axis in cholangiocytes mitigates cholestatic liver injury ...
Zhijian Zheng, Jing Xie, Liman Ma, Zhiqing Hao, Weiwei Zhang, Lihua Li   +5 more
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Comparison of VDR Expression and Blood Vitamin D 1.25 (OH)2 Level between Cervical Cancer Patients and Normal Women

Indonesian Journal of Cancer, 2020
Background: Vitamin D and its receptor (VDR) play a crucial role in the development of gynecological cancers. This study aims to evaluate the VDR expression and blood vitamin D 1.25 (OH)2 levels in cervical cancer patients and healthy women.
Brahmana Askandar, Teuku Mirza Iskandar, Very Great Ekaputra   +2 more
doaj   +1 more source

The Anti-Sepsis Effect of Isocorydine Screened from Guizhou Ethnic Medicine is Closely Related to Upregulation of Vitamin D Receptor Expression and Inhibition of NFκB p65 Translocation into the Nucleus

Journal of Inflammation Research, 2022
Jing Luo,1 Nuoyan Wang,1 Ling Hua,1 Fei Deng,1 Dan Liu,1 Jun Zhou,1 Yue Yuan,1 Fumin Ouyang,1 Xuemin Chen,1 Shujuan Long,1 Yasi Huang,1 Zhanxing Hu,2,3 Hong Zhou1 1Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International ...
Luo J, Wang N, Hua L, Deng F, Liu D, Zhou J, Yuan Y, Ouyang F, Chen X, Long S, Huang Y, Hu Z, Zhou H   +12 more
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Vitamin D receptor expression is essential during retinal vascular development and attenuation of neovascularization by 1, 25(OH)2D3. [PDF]

PLoS ONE, 2017
Vitamin D provides a significant benefit to human health, and its deficiency has been linked to a variety of diseases including cancer. Vitamin D exhibits anticancer effects perhaps through inhibition of angiogenesis. We previously showed that the active
Nasim Jamali, Shoujian Wang, Soesiawati R Darjatmoko, Christine M Sorenson, Nader Sheibani   +4 more
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Ligand-associated activation of vitamin D receptors and potential points of application of its effects in the morphogenesis of immune inflammation: Literature review

Acta Biomedica Scientifica
According to recent data, vitamin D is classified as a substance with hormonal activity, which, in addition to classical, has “non-classical” effects caused by the complex relationship between vitamin D and effector cells of the immune system.
E. T. Ablyakimov, M. A. Kriventsov
doaj   +1 more source