Results 21 to 30 of about 25,277 (207)
The Journal of Poultry Science, 2022 1,25-Dihydroxycholecalciferol (1,25-(OH)2-D3) is the final active product of vitamin D. This study aimed to investigate the effects of 1,25-(OH)2-D3 on growth performance, bone development, and calcium (Ca) transporter gene expression levels in the ...
Lihua Wu +9 more
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Nephrolithiasis in primary hyperparathyroidism: a contemporary look
Ожирение и метаболизм, 2014 Primary hyperparathyroidism (PHPT) has attracted a growing attention of medical doctors of different specialties in the last few years. The ability to predict the risk of the development of visceral manifestations (nephrolithiasis, nephrocalcinosis ...
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Oncotarget, 2015 The active form of vitamin D, 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3; calcitriol], plays a key role in mineral and bone homeostasis, and exerts potent anti-inflammatory and anti-proliferative activities [1]. It is thus a potential pharmacological agent to treat various diseases, including autoimmune disorders, infections and cancer [1].
Laverny, Gilles, Metzger, Daniel
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Association of rs2476601 and rs1544410 with Onset of T1D in Youngsters of Lahore, Pakistan
Journal of Bioresource Management, 2016 The PTPN22 gene plays vital role in T1D onset by encoding Lymphoid-specific phosphatase (LYP) that lead to T-cell receptor-associated CsK kinase inactivation and preventing T-cell spontaneous activation by dephosphorylation.
Andleeb Batool +3 more
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Bile acid dysmetabolism in inflammatory bowel diseases
Alʹmanah Kliničeskoj Mediciny, 2023 Aim: To summarize the state-of-the-art data on the molecular mechanisms of bile acid (BA) synthesis and absorption, their impaired absorption and receptor-dependent signaling, as well as on the effects of the gut microbiota on BA metabolism in ...
Daria A. Kuznetsova +2 more
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Presence of a Truncated Form of the Vitamin D Receptor (VDR) in a Strain of VDR-Knockout Mice [PDF]
Endocrinology, 2005 As part of our studies on the membrane-initiated actions of 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3] and its localization in caveolae membrane fractions, we used a vitamin D receptor (VDR)-knockout (KO) mouse model to study the binding of [3H]-1α,25(OH)2D3 in the presumed absence of the VDR.
Craig M, Bula +5 more
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Diabetes, Metabolic Syndrome and Obesity, 2022 Wenjie Wen,1,2,* Bin Huang,1,2,* Shandong Ye1,2 1Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of University of Science and Technology of China (USTC), Department of Life Sciences and Medicine, University ...
Wen W, Huang B, Ye S
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The role of vitamin D in seasonal acute respiratory viral infections and COVID-19
Терапевтический архив, 2020 A link between vitamin D deficiency and susceptibility to infectious diseases was suggested over a hundred years ago. Epidemiological studies show a strong association between seasonal fluctuations in vitamin D levels and the incidence of various ...
E. A. Pigarova +4 more
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Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2023 Introduction. Vitamin D deficiency may be a natural predictor of the onset of coronary heart disease (CHD) and myocardial infarction (MI) at a young age. The results of studies of the various variants association of the vitamin D receptor (VDR) gene with
O. A. Bercovich +8 more
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The impact of VDR expression and regulation in vivo [PDF]
The Journal of Steroid Biochemistry and Molecular Biology, 2018 The vitamin D receptor (VDR) mediates the pleiotropic biological actions of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). These actions include orchestration of mineral homeostasis which is coordinated by the kidney, intestine, bone and parathyroid gland wherein the VDR transcriptionally regulates expression of the genes involved in this complex process ...
Seong Min, Lee +4 more
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