Results 11 to 20 of about 25,277 (207)

Vitamin D receptor signaling in inflammatory senescence-associated skin aging: Mechanisms and therapeutic potentials. [PDF]

J Cell Commun Signal
Vitamin D receptor (VDR) signaling is implicated in inflammatory senescence‐associated skin aging, a growing health concern in aging populations where cellular senescence and chronic inflammation converge to create complex pathophysiological conditions.
Guan L, Yang F, Li M, Chen Y, Zhao Z, Li H, Luo D, Li Q, Chen Y.   +8 more
europepmc   +2 more sources

Probiotic-Mediated Vitamin D Supplementation Improves the Gut Microbiota and Vitamin D Receptor Composition in Obese Rats. [PDF]

Food Sci Nutr
Lifestyle factors such as regular physical activity, dietary fiber intake, Mediterranean‐style eating patterns, and breastfeeding support gut microbiota balance, whereas Western‐style diets, fast‐food consumption, sugar‐sweetened beverages, and excessive screen time contribute to dysbiosis and obesity.
Kılınç GE, Söğüt MÜ.
europepmc   +2 more sources

Enhancement of VDR-Mediated Transcription by Phosphorylation: Correlation with Increased Interaction Between the VDR and DRIP205, a Subunit of the VDR-Interacting Protein Coactivator Complex [PDF]

Molecular Endocrinology, 2002
When UMR-106 osteoblastic cells, LLCPK1 kidney cells, and VDR transfected COS-7 cells were transfected with the rat 24-hydroxylase [24(OH)ase] promoter (-1,367/+74) or the mouse osteopontin (OPN) promoter (-777/+79), we found that the response to 1,25dihydroxyvitamin D(3) [1,25-(OH)(2)D(3)] could be significantly enhanced 2- to 5-fold by the protein ...
Frank, Barletta, Leonard P, Freedman, Sylvia, Christakos   +2 more
openaire   +3 more sources

Vitamin D and extraskeletal effects [PDF]

Romanian Journal of Medical Practice, 2017
Vitamin D is a fat soluble vitamin and a steroid hormone with endocrine, paracrine and autocrine actions. The two major forms are vitamin D2 (ergocalcifeol) and vitamin D3 (cholecalciferol), the active hormone being calcitriol.
Andra BURUIANĂ, Eugenia NEDELTCHEVAͳPETROVA, Nicoleta DUMITRU, Maria OLARU, Ion COCOLOŞ, Mara CARŞOTE, Adina GHEMIGIAN   +6 more
doaj   +1 more source

Vitamin D Receptor (VDR) Regulation of Voltage-Gated Chloride Channels by Ligands Preferring a VDR-Alternative Pocket (VDR-AP) [PDF]

Molecular Endocrinology, 2011
We have postulated that the vitamin D receptor (VDR) contains two overlapping ligand binding sites, a genomic pocket and an alternative pocket (AP), that mediate regulation of gene transcription and rapid responses, respectively. Flexible VDR + ligand docking calculations predict that the major blood metabolite, 25(OH)-vitamin D3 (25D3), and curcumin ...
Danusa, Menegaz, Mathew T, Mizwicki, Antonio, Barrientos-Duran, Ning, Chen, Helen L, Henry, Anthony W, Norman   +5 more
openaire   +2 more sources

The association of ACE1, ACE2, TMPRSS2, IFITM3 and VDR polymorphisms with COVID-19 severity

EXCLI Journal : Experimental and Clinical Sciences, 2022
Genes involved in the regulation of viral recognition and its entry into a host cell have been identified as candidates for genetic association studies on COVID-19 severity.
Zorana Dobrijević, Dragana Robajac, Nikola Gligorijević, Miloš Šunderić, Ana Penezić, Goran Miljuš, Olgica Nedić   +6 more
doaj   +1 more source

Protective Role of Vitamin D in Renal Tubulopathies

Metabolites, 2020
Vitamin D is tightly linked with renal tubular homeostasis: the mitochondria of proximal convoluted tubule cells are the production site of 1α,25-dihydroxyvitamin D3.
Guido Gembillo, Valeria Cernaro, Rossella Siligato, Francesco Curreri, Antonino Catalano, Domenico Santoro   +5 more
doaj   +1 more source

VDR

Proceedings of the 2nd ACM Conference on Information-Centric Networking, 2015
In this work, we propose VDR, a routing scheme based on virtual domains -- domains that are not bound to physical routers -- to exploit the benefits of aggregation and hashing while overcoming their disadvantages. VDR addresses the FIB scalability issue in CCN by facilitating aggregation without compromising on the advantages of CCN such as ease of ...
Jie Li 0008, Jiachen Chen, Mayutan Arumaithurai, Xingwei Wang 0001, Xiaoming Fu 0001   +4 more
openaire   +3 more sources

Factor analysis of clinical and biochemical parameters of bone remodeling changes associated with leading VDR polymorphisms in patients with aseptic necrosis of the femoral head

Гений oртопедии, 2023
Introduction Bone metabolic markers informatively reflect the complex balance of bone formation/resorption and are widely used in clinical practice. Genetic predisposition also plays a significant role in the etiopathogenesis of aseptic necrosis of the ...
Evgeny E. Volkov, Andrey P. Goloshchapov, Rustam N. Mustafin, Svetlana E. Nostaeva   +3 more
doaj   +1 more source

Association of Single Nucleotide Polymorphisms in the VDR and CYP27B1 Genes with Risk of Developing Vitamin D3 Deficiency

Journal of Pure and Applied Microbiology, 2021
This study was carried out to investigate the relationship between common variants in two vitamin D pathway genes (VDR and CYP27B1) and vitamin D3 serum levels.
Hormoz Selahvarzi, Milad Kamdideh, Mehrnoosh Vahabi, Ali Dezhgir, Massoud Houshmand, Soha Sadeghi   +5 more
doaj   +1 more source