Results 101 to 110 of about 23,299 (273)

Role of Antimicrobial Peptides in the Pathogenesis of Atopic Dermatitis

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by barrier dysfunction, immune dysregulation, and microbial dysbiosis. Recent studies have highlighted the multifaceted roles of antimicrobial peptides (AMPs) both as innate defenders against microbial invasion and as regulators of immune responses and skin barrier ...
Ge Peng, Alafate Abudouwanli, Quan Sun, Yi Tan, Wanchen Zhao, Mengyao Yang, Shan Wang, Hideoki Ogawa, Ko Okumura, François Niyonsaba   +9 more
wiley   +1 more source

The role of vitamin D3 and vitamin B9 (Folic acid) in immune system [PDF]

, 2016
Background and aims: Vitamins are essential constituents of our diet that Longley have been known to influence the immune system. Vitamin D3 and B9 have received particular attention in recent years as these vitamins have been shown to have an unexpected
Mansourabadi, Amir Hossein., Mansouri, Reza., Moogooei, Maryam., Moogooei, Mozhgan., Razavi, Nastaran.   +4 more
core   +1 more source

Sunshine vitamin and thyroid [PDF]

, 2017
Vitamin D exerts its canonical roles on the musculoskeletal system and in the calcium/phosphorus homeostasis. In the last years, increasing evidences suggested several extra-skeletal actions of this hormone, indicating that vitamin D may produce effects ...
ALBANO, LUIGI, COLAO, ANNAMARIA, MACCHIA, PAOLO EMIDIO, NETTORE, IMMACOLATA CRISTINA, UNGARO, PAOLA   +4 more
core   +1 more source

Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis

Allergy, EarlyView.
This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino, Juno Kim, Manru Li, Philipp Gessner, Patrick Westermann, Yagız Pat, Carina Beha, Claudia Traidl‐Hoffmann, Jeremy Bost, Nicolas Gaudenzio, Christoph B. Messner, Cezmi A. Akdis, Yasutaka Mitamura   +12 more
wiley   +1 more source

Calcitriol imparts neuroprotection in vitro to midbrain dopaminergic neurons by upregulating GDNF expression.

PLoS ONE, 2013
During development a tightly controlled signaling cascade dictates the differentiation, maturation and survival of developing neurons. Understanding this signaling mechanism is important for developing therapies for neurodegenerative illnesses.
Rowan P Orme, Manminder S Bhangal, Rosemary A Fricker   +2 more
doaj   +1 more source

New therapies: calcimimetics, phosphate binders and vitamin D receptor activators [PDF]

, 2010
At present, new compounds are available to treat secondary hyperparathyroidism, namely calcimimetics, novel phosphorus binders and also novel vitamin D receptor activactors.
Cannata, J.B. (Jorge), López, Francisco, Rodríguez, Diego, Rodríguez, Minerva, Román-García, Pablo, Tuñón, Diego   +5 more
core  

Recommendations of the Brazilian Society of Endocrinology and Metabology (SBEM) for the diagnosis and treatment of hypovitaminosis D [PDF]

, 2014
ObjectiveThe objective is to present an update on the diagnosis and treatment of hypovitaminosis D, based on the most recent scientific evidence. Materials and methodThe Department of Bone and Mineral Metabolism of the Brazilian Society of Endocrinology ...
Bandeira, Francisco, Borba, Victoria Zeghbi Cochenski, Borges, João Lindolfo Cunha, Camargo, Marília Brasilio Rodrigues, Lazaretti-Castro, Marise, Maeda, Sergio Setsuo, Silva, Dalisbor Marcelo Weber   +6 more
core   +2 more sources

Role of Calcitriol and Vitamin D Receptor (VDR) Gene Polymorphisms in Alzheimer’s Disease

International Journal of Molecular Sciences
Alzheimer’s disease (AD) is characterized by amyloid beta (Aβ) buildup and neuronal degeneration. An association between low serum vitamin D levels and an increased risk of AD has been reported in several epidemiological studies. Calcitriol (1,25-dihydroxycholecalciferol) is the active form of vitamin D, and is generated in the kidney and many other ...
Soon Pyo Jeong, Niti Sharma, Seong Soo A. An   +2 more
openaire   +2 more sources

Aetiological relevance of haematological, biochemical and endocrine parameters on equine odontoclastic tooth resorption and hypercementosis (EOTRH)

Equine Veterinary Journal, EarlyView.
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow, Anna M. Hain, Astrid Bienert‐Zeit   +2 more
wiley   +1 more source

1,25-Dihydroxycholecalciferol with low-calcium diet reduces acute rejection in rat lung allotransplantation [PDF]

, 2017
OBJECTIVES The effect of 1,25-dihydroxycholecalciferol (calcitriol, vitamin D3) with a low-calcium diet on the acute lung allograft rejection in a rat unilateral left lung transplantation model was evaluated.
Grodzki, Tomasz, Gugger, Mathias, Kubisa, Bartosz, Schmid, Ralph Alexander, Stammberger, Uz, Uduehi, Aima Norma   +5 more
core