Revista de la Facultad de Medicina, 2001 Traditionally, vitamin D has been recognized as an endocrine hormone related mainly with calcium homeostasis. Nevertheless striking studies over the past decade have expanded this concept.
Adriana Bermeo +2 more
doaj
Diagnóstico, prevención y tratamiento de la hipovitaminosis D [PDF]
, 2013 Las recomendaciones que hace el panel de expertos redactores de esta Guía se dividen en "fuertes" y "débiles". Una recomendación fuerte (simbolizada con 1) significa que hay evidencia de alta calidad que la respalda y que la mayor parte de los pacientes ...
Fradinger, Erich +4 more
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Calcitriol inhibits advanced glycation end product (AGE)-elicited mesangial cell damage by sequestrated RAGE-NF-κB Signaling [PDF]
, 2015 维生素D是通过与骨，甲状旁腺，肾脏和胃肠道的相互作用调节钙稳态，已经被用来作为糖尿病肾病（DKD）的常规用药。几个临床试验表明，维生素D在糖尿病肾病的治疗中，存在着减少蛋白尿和减缓肾损伤的抗炎作用，但其作用机制尚不清楚。而晚期糖化终产物（AGEs）在血浆和肾的积累，在糖尿病肾病中，是大家公认的促炎症分子。为了探索这种抗炎作用，我们设计实验。 研究目的：探寻骨化三醇减少AGEs引起的人肾系膜细胞炎症反应的机制，具体是探寻骨化三醇对AGEs引起的人系膜细胞表达白细胞介素-6（IL-6）和单核细胞趋化因子 ...
刘波
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Celecoxib in breast cancer prevention and therapy. [PDF]
, 2018 Breast cancer has a high incidence worldwide. The results of substantial studis reveal that inflammation plays an important role in the initiation, development, and aggressiveness of many malignancies. The use of celecoxib, a novel NSAID, is repetitively
Cao, Wei +4 more
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Journal of Orthopaedic TranslationObjective: The effects of vitamins D and K on osteoarthritis (OA) progression remain ambiguous, particularly in its subtype, osteoporotic OA (OPOA), where aberrant activation of osteoclasts exacerbates subchondral bone remodeling.
Yang Zhao +8 more
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Vitamin D receptor and its antiproliferative effect in human pulmonary arterial hypertension
Scientific ReportsVitamin D (vitD) deficiency is frequently observed in patients with pulmonary arterial hypertension (PAH) and, in these patients, low levels of vitD correlate with worse prognosis.
Maria Callejo +13 more
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Role of Vitamin D Receptor in the Antiproliferative Effects of Calcitriol in Tumor-Derived Endothelial Cells and Tumor Angiogenesis In vivo [PDF]
, 2009 Ivy Chung +7 more
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Parathyroid hormone-related peptide and vitamin D in phosphocalcic metabolism for dromedary camel [PDF]
, 2011 In mammals, phosphocalcic and bone metabolisms are mainly regulated by parathyroïd hormone, parathyroïd hormone-related peptide (PTHrP) and 1[alpha],25-dihydroxyvitamin D or calcitriol. In camels, circulating levels of calcitriol are 10 times higher than
El Khasmi, Mohammed, Faye, Bernard
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Calcitriol Inhibits Hedgehog Signaling and Induces Vitamin D Receptor Signaling and Differentiation in thePatchedMouse Model of Embryonal Rhabdomyosarcoma [PDF]
, 2012 Anja Uhmann +9 more
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Calcitriol May Down-Regulate mRNA Over-Expression of Toll-Like Receptor-2 and -4,LL-37and Proinflammatory Cytokines in Cultured Human Keratinocytes [PDF]
, 2014 Mi Sook Jeong +3 more
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