Results 31 to 40 of about 23,587 (266)

Vitamin D, a modulator of musculoskeletal health in chronic kidney disease [PDF]

, 2017
The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD ...
Jordi Bover, Juan J. Carrero, null null, Pablo Molina, Pablo Ureña Torres, Philippe Chauveau, Sandro Mazzaferro   +6 more
core   +2 more sources

Vitamin D receptor genotype influences parathyroid hormone and calcitriol levels in predialysis patients [PDF]

Kidney International, 1999
BsmI vitamin D receptor (VDR) gene polymorphism has been associated with the severity of hyperparathyroidism in patients on hemodialysis. The aim of this study was to analyze the influence of this polymorphism on parathyroid function and serum calcitriol levels in patients with different degrees of chronic renal failure (CRF) before dialysis.A total of
Marco, Maria Paz, Martínez, Isabel, Amoedo, Maria Luisa, Borràs, Mercè, Saracho, Ramón, Almirall, Jaume, Fibla, Joan, Fernández, Elvira   +7 more
openaire   +2 more sources

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Henze, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source

Condylar Bone Quality in Growing Children Is Associated With Genetic Polymorphisms in Genes Involved in Calcium and Phosphate Maintenance. [PDF]

Biomed Res Int
Single nucleotide polymorphisms (SNPs) play a crucial role in regulating vitamin D, parathyroid hormone (PTH), and calcitonin concentrations, which are involved in bone health. Some reports suggested that fractal analysis is useful in the morphometric analysis of the mandible trabecular bone in panoramic radiographs.
Küchler EC, Reis CLB, Fonseca-Souza G, Hemming D, Baratto-Filho F, de Araujo CM, Beisel-Memmert S, Feltrin-Souza J, Meger MN, Cavalcante-Leão BL.   +9 more
europepmc   +2 more sources

Budesonide and Calcitriol Synergistically Inhibit Airway Remodeling in Asthmatic Mice

Canadian Respiratory Journal, 2018
Background and Objective. While calcitriol can inhibit airway remodeling in asthmatic mice, the mechanism remains unclear. The purpose of this study was to explore the mechanism of action of calcitriol on airway remodeling in asthma and its interaction ...
Jun Qian, Yaqin Xu, Zhiwei Yu
doaj   +1 more source

Relationship between adipose tissue dysfunction, Vitamin D deficiency and the pathogenesis of non-alcoholic fatty liver disease [PDF]

, 2017
Non-alcoholic fatty liver disease ( NAFLD) is the most common chronic liver disease worldwide. Its pathogenesis is complex and not yet fully understood.
BARCHETTA, ILARIA, BARONI, Marco Giorgio, BERTOCCINI, LAURA, CAROTTI, Simone, CAVALLO, Maria Gisella, CIMINI, FLAVIA AGATA, Morini, Sergio, VESPASIANI GENTILUCCI, UMBERTO   +7 more
core   +1 more source

Calcitriol Inhibits the Proliferation of Triple-Negative Breast Cancer Cells through a Mechanism Involving the Proinflammatory Cytokines IL-1β and TNF-α

Journal of Immunology Research, 2019
Triple-negative breast cancer (TNBC) is one of the most aggressive tumors, with poor prognosis and high metastatic capacity. The aggressive behavior may involve inflammatory processes characterized by deregulation of molecules related to the ...
Isela Martínez-Reza, Lorenza Díaz, David Barrera, Mariana Segovia-Mendoza, Sigifredo Pedraza-Sánchez, Giovanny Soca-Chafre, Fernando Larrea, Rocío García-Becerra   +7 more
doaj   +1 more source

Calcitriol Suppresses HIF-1 and HIF-2 Transcriptional Activity by Reducing HIF-1/2α Protein Levels via a VDR-Independent Mechanism

Cells, 2020
Hypoxia-inducible transcription factors 1 and 2 (HIFs) are major mediators of cancer development and progression and validated targets for cancer therapy.
Ioanna-Maria Gkotinakou, Eleni Kechagia, Kalliopi Pazaitou-Panayiotou, Ilias Mylonis, Panagiotis Liakos, Andreas Tsakalof   +5 more
doaj   +1 more source

Effect of Calcitriol on the Renal Microvasculature Differentiation Disturbances Induced by AT1 Blockade During Nephrogenesis in Rats

Frontiers in Medicine, 2020
Alterations in the renal vasculature during fetal programming can cause disturbances in renal structure and function that persist into adulthood. Calcitriol can affect cellular differentiation and proliferation, and promote endothelial cell maintenance ...
Amanda L. Deluque, Lucas F. de Almeida, Heloísa D. C. Francescato, Cleonice G. A. da Silva, Roberto S. Costa, José Antunes-Rodrigues, Terezila M. Coimbra   +6 more
doaj   +1 more source

1α,25-dihydroxyvitamin D3 ameliorates seawater aspiration-induced acute lung injury via NF-κB and RhoA/Rho kinase pathways. [PDF]

PLoS ONE, 2014
INTRODUCTION: Inflammation and pulmonary edema are involved in the pathogenesis of seawater aspiration-induced acute lung injury (ALI). Although several studies have reported that 1α,25-Dihydroxyvitamin D3 (calcitriol) suppresses inflammation, it has not
Minlong Zhang, Mingqing Dong, Wei Liu, Li Wang, Ying Luo, Zhichao Li, Faguang Jin   +6 more
doaj   +1 more source