Results 101 to 110 of about 2,988,254 (363)

Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. [PDF]

, 2009
The cause(s) of sporadic Alzheimer's disease (sAD) are complex and currently poorly understood. They likely result from a combination of genetic, environmental, proteomic and lipidomic factors that crucially occur only in the aged brain.
Green, Kim N
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia

Neurobiology of Disease
Excitotoxicity arises from unusually excessive activation of excitatory amino acid receptors such as glutamate receptors. Following an energy crisis, excitotoxicity is a major cause for neuronal death in neurological disorders. Many glutamate antagonists
Charlene P. Poore, Nurul A.M.N. Hazalin, Shunhui Wei, See Wee Low, Bo Chen, Bernd Nilius, Zurina Hassan, Ping Liao   +7 more
doaj   +1 more source

Vitamin D in the Middle East and North Africa

Bone Reports, 2018
Purpose: The Middle East and North Africa (MENA) region registers some of the lowest serum 25‑hydroxyvitamin D [25(OH)D] concentrations, worldwide. We describe the prevalence and the risk factors for hypovitaminosis D, completed and ongoing clinical ...
Marlene Chakhtoura, Maya Rahme, Nariman Chamoun, Ghada El-Hajj Fuleihan   +3 more
doaj   +1 more source

A model study of enhanced oil recovery by flooding with aqueous surfactant solution and comparison with theory [PDF]

, 2015
With the aim of elucidating the details of enhanced oil recovery by surfactant solution flooding, we have determined the detailed behavior of model systems consisting of a packed column of calcium carbonate particles as the porous rock, n-decane as the ...
Clarke, Andrew, Fletcher, Paul D. I., Howe, Andrew M., Savory, Luke D., Woods, Freya   +4 more
core   +2 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Is the Calcium Pump Involved in Calcium Release?

Zeitschrift für Naturforschung C, 1986
The blockage of all thiol residues accessible to the mercurial mersalyl in the sarcoplasmic reticulum membranes resulting in complete inactivation of the membranes’ calcium transport system does interfere neither with caffeine- nor calcium-induced calcium release from actively loaded membrane vesicles.
Ungeheuer, M., Migala, A., Hasselbach, W.   +2 more
openaire   +5 more sources

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Current Situation of Vanadium Resources and New Process Progress of Vanadium Extraction from the Stone Coal Vanadium Ore

Kuangchan zonghe liyong
The main occurrence minerals of vanadium include vanadium titanomagnetite, stone coal vanadium and vanadium lead ores. At present, the vanadium extraction processes of stone coal vanadium ore are mainly sodium roasting-water leaching and calcification ...
Jinwei QU, Na MA, Yuefang HU, Xiaoying WENG, Zhihe DOU   +4 more
doaj   +1 more source

Calcium carbonate-calcium phosphate mixed cement compositions for bone reconstruction [PDF]

, 2006
The feasibility of making calcium carbonate-calcium phosphate (CaCO3-CaP) mixed cements, comprising at least 40 % (w/w) CaCO3 in the dry powder ingredients, has been demonstrated.
Arnaud, Atlan, Blom, Bohic, Bohner, Bohner, Braye, Brecevic, Brown, Cazalbou, Chiroff, Collins, Combes, Constantz, Daculsi, Damien, De Maeyer, dos Santos, Elliott, Fernandez, Fontaine, Ginebra, Guillemin, Hatim, Heughebaert, Heughebaert, Huffman, Ikenaga, Jamali, Khairoun, Kon, Larsen, Legeros, Lucas, Maeda, Meldrum, Mirtchi, Mirtchi, Mosmann, Nillson, Ohura, Oyane, Parish, Penel, Piattelli, Rawlings, Reddy, Rey, Rey, Rey, Rey, Sabbides, Souyris, Tofighi, Vilamitjana-Amédée, Walsh   +55 more
core   +2 more sources