Results 141 to 150 of about 3,765,678 (388)

Is the Calcium Pump Involved in Calcium Release?

open access: yesZeitschrift für Naturforschung C, 1986
The blockage of all thiol residues accessible to the mercurial mersalyl in the sarcoplasmic reticulum membranes resulting in complete inactivation of the membranes’ calcium transport system does interfere neither with caffeine- nor calcium-induced calcium release from actively loaded membrane vesicles.
Ungeheuer, M.   +2 more
openaire   +5 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Studies in calcium metabolism [PDF]

open access: green, 1928
Corbet Page Stewart, G. H. Percival
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

CFTR-mediated anion secretion in parathyroid hormone-treated Caco-2 cells is associated with PKA and PI3K phosphorylation but not intracellular pH changes or Na+/K+-ATPase abundance

open access: yesBiochemistry and Biophysics Reports, 2021
Parathyroid hormone (PTH) has previously been shown to enhance the transepithelial secretion of Cl− and HCO3− across the intestinal epithelia including Caco-2 monolayer, but the underlying cellular mechanisms are not completely understood.
Rattana Chaimana   +7 more
doaj  

Calcium and Phosphorus Deficiencies in Poor Dietary [PDF]

open access: green, 1938
W. E. Gaunt, J. T. Irving, Wendy Thomson
openalex   +1 more source

Voltage-gated calcium channels.

open access: yesCold Spring Harbor Perspectives in Biology, 2011
Voltage-gated calcium (Ca(2+)) channels are key transducers of membrane potential changes into intracellular Ca(2+) transients that initiate many physiological events.
W. Catterall
semanticscholar   +1 more source

CALCIUM METABOLISM AND CALCIUM THERAPY

open access: yesThe American Journal of the Medical Sciences, 1933
Bibliography: p. [185]-200. ; Mode of access: Internet.
openaire   +3 more sources

Sulphide of Calcium [PDF]

open access: yesScientific American, 1876
n ...
openaire   +2 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

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