Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin‐Converting Enzyme Inhibitors and Angiotensin Receptor Blockers [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Elaine Ku +4 more
doaj +3 more sources
Vasorelaxant Effect of a Newly Synthesized Dihydropyridine Ethyl Ester (DHPEE) on Rat Thoracic Aorta: Dual Mechanism of Action [PDF]
Advanced Pharmaceutical Bulletin, 2011 Introduction: DHPEE is a newly synthesized compound by merging the key structural elements in an angiotensin receptor blocker (Telmisartan) with key structural elements in 1,4- dihydropyridine calcium channel blocker (Nifedipine).
Hossein Babaei +4 more
doaj +2 more sources
Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol [PDF]
Case Reports in Medicine, 2011 Introduction. Overdose with the calcium channel blocker amlodipine can cause profound hypotension that may be exacerbated by the concurrent ingestion of an angiotensin II receptor antagonist.
James O. M. Plumb +3 more
doaj +4 more sources
Pharmaceuticals, 2023 Renin-angiotensin system (RAS) inhibitors and calcium channel blockers (CCB) are often used together in chronic kidney disease (CKD). The PubMed, EMBASE, and Cochrane Library databases were searched to identify randomized controlled trials (RCTs) in ...
Mingming Zhao +9 more
doaj +1 more source
Medicine, 2003 Overdose of calcium channel blockers is potentially lethal. Verapamil and diltiazem are much more dangerous than dihydropyridines. Hypotension with (verapamil and diltiazem) or without (dihydropyridines) heart block and bradycardia are the most important features.
Buckley, Nicholas +2 more
openaire +2 more sources
Calcium Channel Blocker Overdose Simulation
MedEdPORTAL, 2015 Introduction Accidental poisoning and drug overdose are a common occurrence in the emergency medicine setting. Often it is unknown what substances the patient has taken.
Michael Maniaci +2 more
doaj +1 more source
Inhibition of Escherichia coli chemotaxis by omega-conotoxin, a calcium ion channel blocker [PDF]
, 1993 Escherichia coli chemotaxis was inhibited by omega-conotoxin, a calcium ion channel blocker. With Tris-EDTA-permeabilized cells, nanomolar levels of omega-conotoxin inhibited chemotaxis without loss of motility.
Adler, Julius +2 more
core +3 more sources
Pre-injury beta blocker use does not affect the hyperdynamic response in older trauma patients
Journal of Emergencies, Trauma and Shock, 2014 Purpose: Trauma dogma dictates that the physiologic response to injury is blunted by beta-blockers and other cardiac medications. We sought to determine how the pre-injury cardiac medication profile influences admission physiology and post-injury ...
David C Evans +8 more
doaj +1 more source
Experts Consensus Recommendations for the Management of Calcium Channel Blocker Poisoning in Adults
Critical Care Medicine, 2017 Objective: To provide a management approach for adults with calcium channel blocker poisoning. Data Sources, Study Selection, and Data Extraction: Following the Appraisal of Guidelines for Research & Evaluation II instrument, initial voting statements ...
M. St-Onge +16 more
semanticscholar +1 more source
JAMA Network Open, 2019 Key Points Question What is the risk of experiencing the prescribing cascade of treating dihydropyridine calcium channel blocker–induced lower-extremity edema with a loop diuretic?
S. Vouri +6 more
semanticscholar +1 more source